Evidence map›Paper›PMID 39726802›Full record

ArticleDNA2024

How Chromatin Motor Complexes Influence the Nuclear Architecture: A Review of Chromatin Organization, Cohesins, and Condensins with a Focus on

Bahaar Chawla, Gyӧrgyi Csankovszki

Abstract read
In one paragraph

Article in DNA, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Bahaar ChawlaDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI 48109-1085, USA.
Gyӧrgyi CsankovszkiDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI 48109-1085, USA.

Funding

The Dosage Compensation Machinery of C. ElegansR01GM079533 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CSANKOVSZKI, GYORGYI · 2007 to 2015
$2.5M
The gene regulatory functions of condensinR35GM149543 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Gyorgyi Csankovszki · 2023 to 2026
$1.8M
Gene regulatory functions of condensinR01GM133858 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CSANKOVSZKI, GYORGYI · 2020 to 2021
$602k
NIGMS NIH HHS R01 GM079533NIGMS NIH HHS R01 GM133858NIGMS NIH HHS R35 GM149543
6 · The paper itself

Abstract

Chromatin is the complex of DNA and associated proteins found in the nuclei of living organisms. How it is organized is a major research field as it has implications for replication, repair, and gene expression. This review summarizes the current state of the chromatin organization field, with a special focus on chromatin motor complexes cohesin and condensin. Containing the highly conserved SMC proteins, these complexes are responsible for organizing chromatin during cell division. Additionally, research has demonstrated that condensin and cohesin also have important functions during interphase to shape the organization of chromatin and regulate expression of genes. Using the model organism

Indexed as

C. eleganschromatin architecturecohesincondensindosage compensationSMC proteinsTADs

Identifiers

PMID39726802
PMCPMC11671135

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.