Evidence map›Paper›PMID 39726798›Full record

ArticleAnnals of clinical epidemiology2024

Evaluating optimal rehabilitation strategies in ICU: study protocol for a multicentre cohort study to assess Physical Activity dosing, Muscle mass, and physICal outcomeS (IPAMICS study).

Yasunari Morita, Shinichi Watanabe, Nobuto Nakanishi, Akihito Tampo, Kenzo Ishii, Keisuke Suzuki, Yoshie Hirota, Yuji Naito, Naoya Sato, Hiroyoshi Yano and 7 more

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In one paragraph

Article in Annals of clinical epidemiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Yasunari MoritaDepartment of Emergency and Intensive Care Medicine, National Hospital Organization, Nagoya Medical Center, Aichi, Japan.
Shinichi WatanabeDepartment of Physical Therapy, Faculty of Rehabilitation, Gifu University of Health science, Gifu, Japan.
Nobuto NakanishiDepartment of Disaster and Emergency Medicine, Graduate School of Medicine, Kobe University, Hyogo, Japan.
Akihito TampoDepartment of Emergency Medicine, Asahikawa Medical University, Hokkaido, Japan.
Kenzo IshiiDepartment of Anesthesiology, Intensive Care Unit, Fukuyama City Hospital, Hiroshima, Japan.
Keisuke SuzukiDepartment of Physical Therapy, Faculty of Rehabilitation, Gifu University of Health science, Gifu, Japan.
Yoshie HirotaDepartment of Rehabilitation, National Hospital Organization, Beppu Medical Center, Oita, Japan.
Yuji NaitoDepartment of Rehabilitation, National Hospital Organization, Shizuoka Medical Center, Shizuoka, Japan.
Naoya SatoDepartment of Rehabilitation, National Hospital Organization, Saitama Hospital, Saitama, Japan.
Hiroyoshi YanoDepartment of Rehabilitation, National Hospital Organization, Saitama Hospital, Saitama, Japan.
Tomohiro YoshikawaDepartment of Rehabilitation Medicine, National Hospital Organization, Hokkaido Medical Center, Hokkaido, Japan.
Atsushi IshiharaRespiratory Support Center, Gifu Prefectural General Medical Center, Gifu, Japan.
Hiroyasu InoueDevision of Physical Therapy Course, Department of Rehabilitation, Showa University School of Nursing and Rehabilitation, Kanagawa, Japan.
Keibun LiuNon-Profit Organization ICU Collaboration Network (ICON), Tokyo, Japan.
Shigeru KobaDepartment of General Internal Medicine, Nerima Hikarigaoka Hospital, Tokyo, Japan.
Kasumi SatohDepartment of Emergency and Critical Care Medicine, Akita University Graduate School of Medicine, Akita, Japan.
Kensuke NakamuraDepartment of Critical Care Medicine, Yokohama City University Hospital, Kanagawa, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany patients who get discharged from the intensive care unit experience physical dysfunction that persists even after discharge. Physical dysfunction is associated with skeletal muscle atrophy and accompanying intensive care unit-acquired weakness in the early stages of intensive care unit admission, and early diagnosis and prevention with early mobilization are crucial. However, the amount of physical activity required for early mobilization remains controversial in critically ill patients. This study aims to reveal the optimal mobilization quantification score dose associated with physical dysfunction after hospital discharge.

methodsThis is a multicenter prospective cohort study planned in 22 facilities; all consecutive patients admitted to the participating facilities between June 2024 and May 2025 will be included. Adult patients on ventilator management for at least 2 days and who will consent to this study will be included. Patients' mobility level and duration will be documented by the mobilization quantification score during their intensive care unit stay, and physical dysfunction will be assessed using muscle mass changes from day one to seven with ultrasonography and the Short-Form 12 Health Survey at 3 months after hospital discharge. The primary outcome is physical dysfunction at 3 months. RESULTS AND

conclusionMobilization quantification score dose and muscle mass evaluation with ultrasonography will enable the quantification of the early mobilization intervention. This study will lay the foundation for future randomised studies.

Indexed as

mobilization quantification score (MQS) dosemuscle mass atrophypost intensive care syndrome (PICS)rectus femoris ultrasonographyShort Form 12 items (SF-12)

Identifiers

PMID39726798
PMCPMC11668687

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.