ArticleThe Lancet regional health. Europe2024
Sex differences in clinically diagnosed psychiatric disorders over the lifespan: a nationwide register-based study in Sweden.
Article in The Lancet regional health. Europe, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
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Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Change of antidepressant utilization in children, adolescents and young adults in Europe before and during the COVID-19 pandemic: a systematic review.European child & adolescent psychiatry · 2026Pooled it
- Moving beyond gender: a systematic review of diversity data gaps in prospective trauma research.European journal of psychotraumatology · 2025Pooled it
- Temporal coupling of cortisol and immune cell responses in acute psychosocial stress.Brain, behavior, & immunity - health · 2026Article
- National prevalence and sociodemographic correlates of potential depression, anxiety, and suicidality among the young population in Kazakhstan: a national population-based study.BMC psychology · 2026Article
- Longitudinal role of sleep disturbance in mental health and functioning among adults with suicidal ideation.The British journal of clinical psychology · 2026Article
- Sexual dimorphism of midbrain catecholaminergic metabolism revealed by neuromelanin-sensitive MRI.Molecular psychiatry · 2026Article
- Frequency and Timing of Depression and Anxiety Diagnoses Following Cancer Diagnosis: A Multi-Center Cohort Study.Cancer medicine · 2026Article
- Sex- and experience-dependent regulation of synaptic protein turnover.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Trends in Psychiatric Presentations Among Children and Adolescents in Alberta: A Pre-/Post-Pandemic Analysis (2017-2022).Child: care, health and development · 2026Article
- Gestational age at birth and the risk of disability pension in early adulthood: a whole-population register study of people born in Finland in 1987-90.International journal of epidemiology · 2026Article
- Gaming disorder symptoms and psychiatric comorbidity from adolescence to early adulthood - a longitudinal study.European child & adolescent psychiatry · 2026Article
- Trends and incidence rates of neurodevelopmental disorders in Danish children and adolescents 2000-2024 : Short title: neurodevelopmental disorders in children and adolescents.European child & adolescent psychiatry · 2026Article
- Clinical and Familial Predictors of Suicidal Ideation and Treatment Outcomes in Hospitalized Adolescents in Turkey: A Retrospective Analysis.Children (Basel, Switzerland) · 2026Article
- Hyperarousal transdiagnostically dissected: different dimensions characterize mood, anxiety, insomnia, posttraumatic stress and attention deficit hyperactivity disorders.EClinicalMedicine · 2026Article
- Assessing key mental health-related lifestyle behaviours and experiences in a single scale: a validation of the Personal Experiences in Everyday Life (PEEL) questionnaire.BMC pediatrics · 2026Article
- Neuroimmune regulation of behavior: Focus on sensory circumventricular organs and associated cell circuit mechanisms.Journal of immunology (Baltimore, Md. : 1950) · 2026Review
- Sex differences in familial risk and genetic components of suicide attempts: a register-based cohort study in Sweden.BMJ mental health · 2026Article
- Psychiatric Disorders Among Fathers in Sweden Before, During, and After Partner Pregnancy.JAMA network open · 2026Article
- Household income and first psychiatric hospital admissions among children and adolescents.The International journal of social psychiatry · 2026Article
- Redesigning medicine: integrating sex and gender for better health outcomes.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Limited studies exist on sex differences in incidence rates of psychiatric disorders across the lifespan. This study aims to analyze sex differences in the incidence rates of clinically diagnosed psychiatric disorders over the lifespan. Methods: We conducted a nationwide register-based cohort study, including all individuals who were born in Sweden and lived in Sweden between 2003 and 2019, including 4,818,071 females and 4,837,829 males. We calculated sex- and age-specific standardized incidence rates for any and 10 major types of psychiatric disorders. Multivariable-adjusted incidence rate differences (IRDs) for diagnosed psychiatric disorders between females and males were estimated. Findings: During a follow-up of 119,420,908 person-years, males showed a higher incidence rate of any diagnosed psychiatric disorder than females at age 5-9 (IRD = -8.93; 95% CI: -9.08 to -8.79; per 1000 person-years), whereas females showed a higher rate than males at age 15-19 (IRD = 9.33; 95% CI: 9.12-9.54) and onwards (except age 60-69). Specifically, among females, excess rates were apparent for depressive, anxiety, eating, stress-related and bipolar disorders at age 10-54, whereas among males, excess rates were pronounced for autism and attention deficit hyperactivity disorders before age 14, drug use disorders at age 15-54, and alcohol use disorders in adulthood. For schizophrenia, the male excess at age 15-49 shifted to female excess at age 60-79. The magnitude of IRDs were greater in recent years and individuals with lower socioeconomic status. Interpretation: Knowledge about the lifespan and socioeconomic variations in the sex differences in rates of diagnosed psychiatric disorders may inform targeted screening/intervention strategies. Funding: Vetenskapsrådet, FORTE, Karolinska Institutet Strategic Research Area in Epidemiology and Biostatistics, and Icelandic Research Fund.
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