Evidence map›Paper›PMID 39726717›Full record

ReviewFrontiers in cell and developmental biology2024

Stem cells and bio scaffolds for the treatment of cardiovascular diseases: new insights.

Zahra Sadat Razavi, Simin Farokhi, Golnaz Mahmoudvand, Arian Karimi-Rouzbahani, Bahareh Farasati-Far, Samaneh Tahmasebi-Ghorabi, Hamidreza Pazoki-Toroudi, Masoud Saadat-Fakhr, Hamed Afkhami

Abstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. The role of stem cells in precision medicine: next-generation cancer treatment.Journal of the Egyptian National Cancer Institute · 2025
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Research progress of stem cells in the treatment of atherosclerosis.Frontiers in cell and developmental biology · 2025
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zahra Sadat RazaviPhysiology Research Center, Iran University of Medical Sciences, Tehran, Iran.
Simin FarokhiStudent Research Committee, USERN Office, Lorestan University of Medical Sciences, Khorramabad, Iran.
Golnaz MahmoudvandStudent Research Committee, USERN Office, Lorestan University of Medical Sciences, Khorramabad, Iran.
Arian Karimi-RouzbahaniStudent Research Committee, USERN Office, Lorestan University of Medical Sciences, Khorramabad, Iran.
Bahareh Farasati-FarDepartment of Chemistry, Iran University of Science and Technology, Tehran, Iran.
Samaneh Tahmasebi-GhorabiMaster of Health Education, Research Expert, Clinical Research Development Unit, Emam Khomeini Hospital, Ilam University of Medical Sciences, Ilam, Iran.
Hamidreza Pazoki-ToroudiPhysiology Research Center, Iran University of Medical Sciences, Tehran, Iran.
Masoud Saadat-FakhrFaculty of Medicine, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran.
Hamed AfkhamiCellular and Molecular Research Center, Qom University of Medical Sciences, Qom, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mortality and morbidity from cardiovascular diseases are common worldwide. In order to improve survival and quality of life for this patient population, extensive efforts are being made to establish effective therapeutic modalities. New treatment options are needed, it seems. In addition to treating cardiovascular diseases, cell therapy is one of the most promising medical platforms. One of the most effective therapeutic approaches in this area is stem cell therapy. In stem cell biology, multipotent stem cells and pluripotent stem cells are divided into two types. There is evidence that stem cell therapy could be used as a therapeutic approach for cardiovascular diseases based on multiple lines of evidence. The effectiveness of stem cell therapies in humans has been studied in several clinical trials. In spite of the challenges associated with stem cell therapy, it appears that resolving them may lead to stem cells being used in cardiovascular disease patients. This may be an effective therapeutic approach. By mounting these stem cells on biological scaffolds, their effect can be enhanced.

Indexed as

bio scaffoldcardiovascular heart diseasecell therapyheart failurestem cell

Identifiers

PMID39726717
PMCPMC11669526

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.