Loeys-Dietz Syndrome Presenting with an Abdominal Aortic Aneurysm: A Case Report.

Kazuki Tsukuda, Yohei Yamamoto, Ai Kazama, Yoshiki Wada, Hiroki Uchiyama, Toru Kikuchi, Toshifumi Kudo

Abstract readCase Reports

In one paragraph

Article in Annals of vascular diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Kazuki TsukudaDivision of Vascular Surgery, Department of Cardiovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.ORCID https://orcid.org/0009-0000-9182-9305

Yohei YamamotoDivision of Vascular Surgery, Department of Cardiovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.ORCID https://orcid.org/0000-0001-9838-3211

Ai KazamaDivision of Vascular Surgery, Department of Cardiovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.

Yoshiki WadaDivision of Vascular Surgery, Department of Cardiovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.ORCID https://orcid.org/0009-0004-4408-7176

Hiroki UchiyamaDivision of Vascular Surgery, Department of Cardiovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.

Toru KikuchiDivision of Vascular Surgery, Department of Cardiovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.

Toshifumi KudoDivision of Vascular Surgery, Department of Cardiovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.ORCID https://orcid.org/0000-0003-3444-8842

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Loeys-Dietz syndrome (LDS) is a genetic connective tissue disorder associated with vascular involvement and craniofacial, skeletal, and cutaneous abnormalities. Herein, we describe the case of a 28-year-old female who presented with a pulsatile mass in her abdomen. Imaging studies revealed multiple aneurysms, including a 53-mm abdominal aortic aneurysm (AAA) and tortuosity of the intracranial arterial vasculature. Genetic testing revealed a mutation in transforming growth factor beta receptor 1, leading to a diagnosis of LDS. The patient underwent open surgical repair of AAA. Other arterial lesions were carefully followed. This case demonstrates that AAA can be a primary manifestation of LDS.

Indexed as

abdominal aortic aneurysmLoeys–Dietz syndromeopen surgical repair

Identifiers

PMID39726561

DOI10.3400/avd.cr.24-00098

PMCPMC11669019

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.