Evidence map›Paper›PMID 39726219›Full record

SynthesisScience progress

Prevalence of cardiovascular instability during hemodialysis therapy in hospitalized patients: A systematic review and meta-analysis.

Karla Arcentales-Vera, María Fernanda Vera-Mendoza, Cristian Cevallos-Salas, María Fernanda García-Aguilera, Luis Fuenmayor-González

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karla Arcentales-VeraPostgrado en Medicina Crítica y Terapia Intensiva, Facultad de Ciencias Médicas, Universidad Central del Ecuador, Quito, Ecuador.
María Fernanda Vera-MendozaPostgrado en Medicina Crítica y Terapia Intensiva, Facultad de Ciencias Médicas, Universidad Central del Ecuador, Quito, Ecuador.
Cristian Cevallos-SalasPostgrado en Medicina Crítica y Terapia Intensiva, Facultad de Ciencias Médicas, Universidad Central del Ecuador, Quito, Ecuador.
María Fernanda García-AguileraPostgrado en Medicina Crítica y Terapia Intensiva, Facultad de Ciencias Médicas, Universidad Central del Ecuador, Quito, Ecuador.
Luis Fuenmayor-GonzálezPostgrado en Medicina Crítica y Terapia Intensiva, Facultad de Ciencias Médicas, Universidad Central del Ecuador, Quito, Ecuador.ORCID 0000-0001-6141-7692

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntradialytic hypotension (IDH) is a common and serious complication in renal replacement therapy, especially in hospitalized patients. The absence of a standardized definition complicates data synthesis and the development of evidence-based guidelines. Current definitions vary, including different blood pressure thresholds, clinical symptoms, and the need for medical intervention during dialysis. IDH is linked to increased mortality and cardiovascular morbidity and may impede renal recovery in patients with acute kidney injury and chronic kidney disease.

methodsA systematic review was conducted using MEDLINE via PubMed, Embase, and Web of Science to identify studies reporting IDH prevalence. A meta-analysis of proportions was performed to determine the global prevalence of IDH, with subgroup analyses to explore heterogeneity. The Joanna Briggs Institute's checklist was used to assess the risk of bias in prevalence studies. The PRISMA guidelines were followed to report the results of this study, PROSPERO registration number CRD42024500622.

resultsThe meta-analysis found a global IDH prevalence of 31% (95% CI 0.18-0.44) across nine studies. Significant heterogeneity was observed (I²: 97.87%;

conclusionsIDH is a significant complication during hospital-based renal replacement therapy, with a global prevalence of 31%. These findings highlight the need for a standardized, evidence-based definition of IDH to improve diagnostic consistency and clinical outcomes through more accurate diagnosis, better treatment strategies, and tailored patient management.

Indexed as

HospitalizationHypotensionRenal DialysisHumansPrevalencecardiovascular instabilityDialysisintradialytic hypotensionproportions meta-analysissystematic review

Identifiers

PMID39726219
PMCPMC11686621

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.