Evidence map›Paper›PMID 39726203›Full record

SynthesisAsian journal of andrology2026

Perioperative therapies and techniques to enhance penile dimensional and functional outcomes following inflatable penile prosthesis implantation: a contemporary 10-year systematic review.

Jan Łaszkiewicz, Ettore De Berardinis, Wojciech Krajewski, Łukasz Nowak, Tomasz Szydełko, Dalila Carino, Vincenzo Asero, Roberta Corvino, Carlo Maria Scornajenghi, Gabriele Savarese and 14 more

Abstract readSystematic Review
In one paragraph

Synthesis in Asian journal of andrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Update on penile prosthesis.Asian journal of andrology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Jan ŁaszkiewiczUniversity Center of Excellence in Urology, Wroclaw Medical University, Wroclaw 50-556, Poland.
Ettore De BerardinisDepartment of Maternal Infant and Urologic Sciences, "Sapienza" University of Rome, Policlinico Umberto I Hospital, Rome 00161, Italy.
Wojciech KrajewskiUniversity Center of Excellence in Urology, Department of Minimally Invasive and Robotic Urology, Wroclaw Medical University, Wroclaw 50-556, Poland.
Łukasz NowakUniversity Center of Excellence in Urology, Department of Minimally Invasive and Robotic Urology, Wroclaw Medical University, Wroclaw 50-556, Poland.
Tomasz SzydełkoUniversity Center of Excellence in Urology, Wroclaw Medical University, Wroclaw 50-556, Poland.
Dalila CarinoDepartment of Maternal Infant and Urologic Sciences, "Sapienza" University of Rome, Policlinico Umberto I Hospital, Rome 00161, Italy.
Vincenzo AseroDepartment of Maternal Infant and Urologic Sciences, "Sapienza" University of Rome, Policlinico Umberto I Hospital, Rome 00161, Italy.
Roberta CorvinoDepartment of Maternal Infant and Urologic Sciences, "Sapienza" University of Rome, Policlinico Umberto I Hospital, Rome 00161, Italy.
Carlo Maria ScornajenghiDepartment of Maternal Infant and Urologic Sciences, "Sapienza" University of Rome, Policlinico Umberto I Hospital, Rome 00161, Italy.
Gabriele SavareseDepartment of Maternal Infant and Urologic Sciences, "Sapienza" University of Rome, Policlinico Umberto I Hospital, Rome 00161, Italy.
Gabriele BignanteDepartment of Urology, Rush University, Chicago, IL 60612, USA.
Felice CrocettoDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples 80131, Italy.
Matteo FerroDepartment of Urology, European Institute of Oncology (IEO), IRCCS, Milan 20141, Italy.
Bernardo RoccoDepartment of Life Sciences, University of Milan, Milan 20122, Italy.
Maria Chiara SighinolfiUrologic Unit, ASST Santi Paolo and Carlo, Milan 20142, Italy.
Shufeng LiDepartment of Urology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Chiyuan Amy ZhangDepartment of Urology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Satvir BasranDepartment of Urology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Anthony MulloyDepartment of Urology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Frank GloverDepartment of Urology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Michael ScottDepartment of Urology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Albert Sangji HaDepartment of Urology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Michael L EisenbergDepartment of Urology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Francesco Del GiudiceDepartment of Maternal Infant and Urologic Sciences, "Sapienza" University of Rome, Policlinico Umberto I Hospital, Rome 00161, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Implantation of inflatable penile prosthesis should be considered as a definitive treatment of erectile dysfunction. However, the sole procedure might not allow for optimal dimensional and functional outcomes. The aim of this study was to systematically review the literature and present the findings on the optimal choice of perioperative methods, surgical techniques, and pharmacotherapy to improve penile length, curvature, and erectile function. Fifteen studies and 697 men were included. Nine studies focused on intraoperative techniques only, while 6 described intra- and postoperative methods. Regarding the outcomes, curvature of the penis was reported in 12 studies, penile length in 5 studies, penile girth in 2 studies, and the International Index of Erectile Function-5 (IIEF-5) score in 7 studies. According to this systematic review, extreme angulation can be reduced using plaque/corporal incisions and grafting with collagen fleece, as well as "scratch" technique with postoperative vacuum therapy. Also, among patients with preoperative curvature of approximately 30°-40°, penile plication, corporoplasty, tunica expansion procedure, manual, and at-home modeling can provide good results. In addition, corporal incisions plus grafting, as well as postoperative vacuum therapy might be the most beneficial in terms of length improvement. Importantly, penile implant in combination with the sealing, daily, and early prosthesis activation proved to improve length. Moreover, postoperative vacuum therapy has also been shown to greatly increase penile circumference. Finally, penile implant in combination with the sealing, corporal incisions plus grafting, "scratch" technique, vacuum therapy, and phosphodiesterase-5 inhibitor are all associated with major improvements in sexual function.

Indexed as

Erectile DysfunctionPenile ImplantationPenile ProsthesisPenisPerioperative CareHumansMaleTreatment Outcomedimensional outcomeserectile functionIIEF-5inflatable penile prosthesispenile curvatureperioperative therapiesPeyronie’s disease

Identifiers

PMID39726203
PMCPMC12912744

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.