Evidence map›Paper›PMID 39726163›Full record

ArticleJournal of gastroenterology and hepatology2025

Asia-Pacific Survey on the Management of Helicobacter pylori Infection.

Koji Otani, Dao Viet Hang, Rapat Pittayanon, Henry Liu, Kee Huat Chuah, John Hsiang, Ning Zhang, Akira Higashimori, Yasuhiro Fujiwara, Upper GI Focus Group of the APAGE‐ELC

Abstract read
In one paragraph

Article in Journal of gastroenterology and hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Dyspepsia followingWorld journal of gastroenterology · 2026
    Article
  3. Article
  4. Asia-Pacific Survey on the Management of Helicobacter pylori Infection.Journal of gastroenterology and hepatology · 2025
    Article
  5. Therapeutics and clinical risk management · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Koji OtaniDepartment of Gastroenterology, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan.ORCID https://orcid.org/0000-0001-9075-6415
Dao Viet HangInternal Medicine Faculty, Hanoi Medical University, Hanoi, Vietnam.
Rapat PittayanonInternal Medicine, King Chulalongkorn Memorial Hospital and Chulalongkorn University, Bangkok, Thailand.ORCID https://orcid.org/0000-0001-6407-5245
Henry LiuDepartment of Medicine, Queen Elizabeth Hospital, Hong Kong.
Kee Huat ChuahGastroenterology and Hepatology Unit, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0001-9811-7546
John HsiangRichmond Gastroenterology Centre, Mount Elizabeth Medical Centre, Singapore.
Ning ZhangDepartment of Gastroenterology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Akira HigashimoriDepartment of Gastroenterology, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan.ORCID https://orcid.org/0000-0002-9950-9899
Yasuhiro FujiwaraDepartment of Gastroenterology, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan.
Upper GI Focus Group of the APAGE‐ELC

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimGastric cancer (GC)-related incidence and mortality rates remain high owing to Helicobacter pylori infection in Asia, and the importance of primary and secondary prevention of GC has been well recognized. We aimed to investigate the extent of overall agreement among clinicians in the Asia-Pacific region regarding the management of H. pylori infection.

methodsThe Upper Gastrointestinal (GI) Focus Group of the Asian Pacific Association of Gastroenterology-Emerging Leaders Committee developed an international survey, which was distributed to 98 clinicians in the Asia-Pacific region, compromising an online questionnaire focusing on the management of H. pylori infection.

resultsParticipants responded from Japan (15, 15.3%), Hong Kong (15, 15.3%), Thailand (33, 33.7%), Vietnam (23, 23.5%), Malaysia (4, 4.1%), Singapore (3, 3.1%), and others (5, 5.1%). The most common first-line eradication regimen was clarithromycin (CAM) triple therapy, including proton pump inhibitor (PPI), amoxicillin (AMPC), and CAM (64.3%) for 14 days (70.4%). The most common second-line eradication regimen was levofloxacin (LVX) triple therapy, including PPI, AMPC, and LVX (22.4%) for 14 days (67.3%). Eradication therapy was deemed necessary for all asymptomatic adults and minors (aged ≤ 17 years) currently infected with H. pylori by 81.6% and 64.3% of respondents, respectively, with 82.7% considering upper GI endoscopy for GC screening useful in the secondary prevention of GC.

conclusionThere appears to be a growing consensus among clinicians, acknowledging the necessity of eradication therapy. We anticipate that this study will establish a new benchmark in preventive medicine aimed at eradicating GC in the Asia-Pacific region.

Indexed as

Anti-Bacterial AgentsHelicobacter InfectionsHelicobacter pyloriPractice Patterns, Physicians'AdultAmoxicillinAsiaClarithromycinDrug Therapy, CombinationFemaleHumansLevofloxacinMaleMiddle AgedProton Pump InhibitorsStomach NeoplasmsAmoxicillinAnti-Bacterial AgentsClarithromycinLevofloxacinProton Pump InhibitorsAsia‐Pacific regiongastric cancerHelicobacter pyloriprimary preventionsecondary prevention

Identifiers

PMID39726163
PMCPMC11968153

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.