Evidence map›Paper›PMID 39726149›Full record

ArticleJournal of medicinal chemistry2025

Design of Small Non-Peptidic Ligands That Alter Heteromerization between Cannabinoid CB

Minos-Timotheos Matsoukas, Marc Ciruela-Jardí, Maria Gallo, Sergi Ferre, David Andreu, Vicent Casadó, Leonardo Pardo, Estefanía Moreno

Abstract read
In one paragraph

Article in Journal of medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Minos-Timotheos MatsoukasDepartment of Biomedical Engineering, University of West Attica, Ag. Spyridonos, Egaleo 12243, Greece.ORCID 0000-0002-4642-8163
Marc Ciruela-JardíLaboratori de Medicina Computacional, Unitat de Bioestadística, Facultat de Medicina, Universitat Autónoma de Barcelona, Bellaterra 08193, Spain.ORCID 0009-0001-9920-8789
Maria GalloDepartment of Medicine and Life Sciences (MELIS-UPF), Universitat Pompeu Fabra, Barcelona 08003, Spain.ORCID 0000-0001-9099-7235
Sergi FerreIntegrative Neurobiology Section, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224, United States.ORCID 0000-0002-1747-1779
David AndreuDepartment of Medicine and Life Sciences (MELIS-UPF), Universitat Pompeu Fabra, Barcelona 08003, Spain.ORCID 0000-0002-6317-6666
Vicent CasadóDepartment of Biochemistry and Molecular Biomedicine, Faculty of Biology, Institute of Biomedicine of the University of Barcelona (IBUB),University of Barcelona, Barcelona 08028, Spain.ORCID 0000-0002-1764-3825
Leonardo PardoLaboratori de Medicina Computacional, Unitat de Bioestadística, Facultat de Medicina, Universitat Autónoma de Barcelona, Bellaterra 08193, Spain.ORCID 0000-0003-1778-7420
Estefanía MorenoDepartment of Biochemistry and Molecular Biomedicine, Faculty of Biology, Institute of Biomedicine of the University of Barcelona (IBUB),University of Barcelona, Barcelona 08028, Spain.ORCID 0000-0002-2491-5753

Funding

Neurotransmitter Receptor Heteromers in the Striatal Spine ModuleZIADA000493 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI FERRE, SERGI · 2009 to 2025
$35.6M
Intramural NIH HHS ZIA DA000493
6 · The paper itself

Abstract

Activation of cannabinoid CB

Indexed as

Drug DesignReceptor, Cannabinoid, CB1Receptor, Serotonin, 5-HT2AAnimalsHEK293 CellsHumansLigandsProtein MultimerizationSmall Molecule LibrariesStructure-Activity RelationshipLigandsReceptor, Cannabinoid, CB1Receptor, Serotonin, 5-HT2ASmall Molecule Libraries

Identifiers

PMID39726149
PMCPMC11726681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.