Evidence map›Paper›PMID 39725780›Full record

ReviewHeart failure reviews2025

Exercise and cardiac rehabilitation after LVAD implantation.

Emily Newman, Yevgeniy Brailovsky, Indranee Rajapreyar

Abstract readReview
In one paragraph

Review in Heart failure reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emily NewmanDivision of Cardiology, Jefferson Heart Institute, Sidney Kimmel School of Medicine, Thomas Jefferson University, 833 Chestnut Street, Suite 630, Philadelphia, PA, 19107, USA. emily.j.newman1@gmail.com.ORCID 0009-0007-9941-2556
Yevgeniy BrailovskyDivision of Cardiology, Jefferson Heart Institute, Sidney Kimmel School of Medicine, Thomas Jefferson University, 833 Chestnut Street, Suite 630, Philadelphia, PA, 19107, USA.
Indranee RajapreyarDivision of Cardiology, Tufts Medical Center, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Left ventricular assist devices (LVAD) have improved mortality and quality of life for patients with end-stage heart failure by providing an alternative to cardiac transplant or as a bridge to transplantation. The improvement in functional capacity however is minimal to modest depending on the right ventricular function, optimal hemodynamics on LVAD therapy, and comorbidities. There is improvement in submaximal exercise capacity but improvement in peak aerobic capacity is limited. Exercise capacity can be improved by referral to cardiac rehabilitation after LVAD implantation. Cardiac rehabilitation is safe and effective with improvement in functional capacity, and decrease in mortality and heart failure hospitalizations. Cardiopulmonary exercise testing (CPET) is a specialized exercise stress test that measures gas exchange during exercise to determine a variety of variables that have been shown to be predictive of mortality in patients undergoing cardiac transplant. CPET is valuable for prognostication and is a predictor of adverse outcomes, including right heart failure in the immediate post-LVAD implantation period, long-term mortality. CPET is an additional testing that can aid in the decision making for LVAD explantation or decommissioning.

Indexed as

Cardiac RehabilitationExercise TherapyHeart-Assist DevicesHeart FailureExercise TestExercise ToleranceHumansQuality of LifeCardiopulmonary exercise testingEnd-stage heart failureLeft ventricular assist devices

Identifiers

PMID39725780
PMCPMC11991995

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.