Evidence map›Paper›PMID 39725751›Full record

ArticlePediatric surgery international2024

Risk factors and surgical outcomes in pediatric patients with congenital heart disease and ischemic colitis.

N Mokhaberi, E P Schneider, M Aftzoglou, I Hüners, M Körner, L Armbrust, D Biermann, R Kozlik-Feldmann, M Hübler, K Reinshagen and 1 more

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Article in Pediatric surgery international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

N MokhaberiDepartment of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. nariman.mokhaberi@uke.de.
E P SchneiderUniversity Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
M AftzoglouDepartment of Paediatric Surgery, Norfolk and Norwich University Hospital, Norwich, UK.
I HünersDepartment of Congenital and Pediatric Heart Surgery, University Heart & Vascular Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
M KörnerDepartment of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
L ArmbrustDepartment of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
D BiermannDepartment of Congenital and Pediatric Heart Surgery, University Heart & Vascular Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
R Kozlik-FeldmannUniversity Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
M HüblerDepartment of Congenital and Pediatric Heart Surgery, University Heart & Vascular Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
K Reinshagen *Department of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
C Tomuschat *Department of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study investigates risk factors and surgical outcomes in pediatric patients with congenital heart defects (CHD) who develop ischemic colitis (IC). Previous research indicates a higher IC risk in very low birth weight neonates with CHD.

methodsA retrospective analysis compared an IC-CHD group to a CHD-only group. Key variables included gestational age, birth weight, multiple pregnancies, prematurity, APGAR scores, cardiac and surgical characteristics, Aristotle-Score, and mortality rates. Surgical outcomes such as bowel resection and stoma procedures were also evaluated.

resultsIC-CHD exhibited significantly lower gestational ages and birth weights, with higher rates of multiple pregnancies and prematurity. APGAR scores were notably lower. Cardiac and surgical data showed more frequent ECMO use and shorter cardiopulmonary bypass durations in the IC-CHD group. High rates of bowel resection highlighted severe gastrointestinal involvement. Mortality was significantly higher in IC-CHD with elevated Aristotle scores correlating with poorer outcomes.

conclusionGestational age, birth weight, and initial health status are critical in predicting IC risk and surgical outcomes in pediatric patients with CHD. The significantly higher mortality and complex surgical needs in the IC-CHD group underscore the necessity for vigilant monitoring and tailored interventions. Development of targeted therapeutic strategies adjustment for confounding factors in future studies is needed.

Indexed as

Colitis, IschemicHeart Defects, CongenitalBirth WeightFemaleGestational AgeHumansInfantInfant, NewbornMaleRetrospective StudiesRisk FactorsTreatment OutcomeBowel ischemiaCongenital heart defectIschemic colitisNecrotizing enterocolitisPediatric

Identifiers

PMID39725751
PMCPMC11671421

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