Evidence map›Paper›PMID 39725620›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2024

[Electroacupuncture improves learning and memory function and promotes hippocampal synaptic regeneration in rats with cerebral ischemia-reperfusion injury].

Ruhui Lin, Jinyan Xia, Xiaohan Ma, Zuanfang Li

Abstract readEnglish Abstract
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. [Electroacupuncture improves post-traumatic stress disorder in rats by alleviating hippocampal mitochondrial injuryNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ruhui LinInnovation and Transformation Center, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Jinyan XiaAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Xiaohan MaAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Zuanfang LiInnovation and Transformation Center, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.

Funding

National Natural Science Foundation of China 81774386
6 · The paper itself

Abstract

objectivesTo explore the neuroprotective mechanism of electroacupuncture at the acupoints

methodsForty-eight male SD rats were equally randomized into sham operation group, cerebral IR model group, acupoint electroacupuncture group and non-acupoint acupuncture group. In the latter 3 groups, cerebral focal ischemic injury was induced using the Longa method; in the two electroacupuncture groups, electroacupuncture was performed either at the acupoints

resultsCompared with those in cerebral IR model group, the rats receiving electroacupuncture at the acupoints, but not those with electroacupuncture at the non-acupoints, showed significantly decreased neurological deficit scores and cerebral infarction volume with shortened escape latency and increased platform crossings. Electroacupuncture at the acupoints significantly increased neuronal cell number, decreased the width of the synaptic gaps and increased density of synaptic bodies in the ischemic hippocampal CA1 area, resulting also in increased serum GABA levels and hippocampal expressions of GABA

conclusionsElectroacupuncture at

Indexed as

Brain IschemiaElectroacupunctureHippocampusMemoryRats, Sprague-DawleyReperfusion InjuryAcupuncture PointsAnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 2Disks Large Homolog 4 Proteingamma-Aminobutyric AcidLearningMaleRatsReceptors, GABA-ASynapsesCalcium-Calmodulin-Dependent Protein Kinase Type 2Disks Large Homolog 4 ProteinDlg4 protein, ratgamma-Aminobutyric AcidReceptors, GABA-Acerebral ischemia-reperfusion injuryelectroacupuncturelearning and memory functionsynaptic plasticitysynaptic regeneration

Identifiers

PMID39725620
PMCPMC11683340

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.