ArticleBMJ open2024
Longitudinal cholesterol trends across socioeconomic groups in Norway: the influence of lipid-lowering drugs in the population-based Tromsø Study 1994-2016.
Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThere is limited evidence regarding the impact of lipid-lowering drugs (LLDs) on the socioeconomic gradient in a longitudinal perspective. The study investigates the longitudinal socioeconomic gradient in total cholesterol levels and whether this is affected by the use of LLDs.
designPopulation-based cohort study.
settingSample from adult inhabitants of Tromsø municipality, Norway, who participated in the Tromsø Study (1994-2016).
participants17 550 participants of the population-based Tromsø Study in 1994-1995 who were non-users of LLD, aged 25-78 years at baseline and who attended one or more of three subsequent surveys in 2001, 2007-2008 and 2015-2016 were included in the study. OUTCOME MEASURE: Socioeconomic gradient in total cholesterol levels was compared among participants treated and not treated with LLDs during the observation period.
resultsThe total cholesterol levels across all educational groups increased from 1994-1995 to 2015-2016 among untreated women (+0.33 mmol/L to +0.48 mmol/L), except for those with primary education (-0.12 mmol/L). Total cholesterol levels decreased among untreated men (-0.40 mmol/L to -0.06 mmol/L, from lowest education to highest education), treated women (-1.88 mmol/L to -1.35 mmol/L) and men (-2.21 mmol/L to -1.84 mmol/L) across all educational groups. At baseline, we observed a significant inverse association between education and total cholesterol levels among non-users of LLDs. There was no clear educational gradient in total cholesterol levels among users of LLDs.
conclusionsUsers of LLDs experienced a more substantial decrease in total cholesterol levels over time compared with non-users. The educational gradient in total cholesterol levels observed among non-users of LLD was not apparent among users.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.