Evidence map›Paper›PMID 39725405›Full record

ArticleJournal of movement disorders2025

A Practical Guide for Diagnostic Investigations and Special Considerations in Patients With Huntington's Disease in Korea.

Jangsup Moon, Eungseok Oh, Minkyeong Kim, Ryul Kim, Dallah Yoo, Chaewon Shin, Jee-Young Lee, Jong-Min Kim, Seong-Beom Koh, Manho Kim and 1 more

Abstract read
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In one paragraph

Article in Journal of movement disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jangsup MoonDepartment of Neurology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Eungseok OhDepartment of Neurology, Chungnam National University Hospital, Daejeon, Korea.
Minkyeong KimDepartment of Neurology, Gyeongsang National University Hospital, Jinju, Korea.
Ryul KimDepartment of Neurology, SMG-SNU Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea.
Dallah YooDepartment of Neurology, Kyung Hee University Hospital, Kyung Hee University School of Medicine, Seoul, Korea.
Chaewon ShinDepartment of Neurology, Chungnam National University College of Medicine, Daejeon, Korea.
Jee-Young LeeDepartment of Neurology, SMG-SNU Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea.
Jong-Min KimDepartment of Neurology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Seong-Beom KohDepartment of Neurology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
Manho KimDepartment of Neurology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Beomseok JeonDepartment of Neurology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

Funding

Chungnam National University Sejong Hospital 2023-S2-008Seoul Metropolitan Government-Seoul National University Boramae Medical Center 04-2022-0014
6 · The paper itself

Abstract

This review provides a comprehensive framework for the diagnostic approach and management of Huntington's disease (HD) tailored to the Korean population. Key topics include genetic counseling, predictive testing, and reproductive options like preimplantation genetic testing. Strategies for assessing disease progression in premanifest HD through laboratory investigations, biofluid, and imaging biomarkers are highlighted. Special considerations for juvenile and late-onset HD, along with associated comorbidities like diabetes mellitus, hypertension, and cardiovascular abnormalities, are discussed. The guide emphasizes personalized symptom management, including pharmacotherapy, physical therapy, and nutritional support, while exploring emerging disease-modifying treatments. A multidisciplinary care model is advocated to improve outcomes for HD patients and caregivers in Korea.

Indexed as

BiomarkerComorbiditiesGenetic counselingHuntington’s diseaseLaboratory investigationsManagementPremanifest

Identifiers

PMID39725405
PMCPMC11824489

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.