Evidence map›Paper›PMID 39724517›Full record

ArticleCancer reports (Hoboken, N.J.)2024

Low Incidence of Cancer Recorded in the Galapagos Archipelago.

Stefano Nicolas Chisesi, Massimo Rugge, Giulia Raffaella Galli, Martina Manni, Veronica Mishell Luzuriaga Delgado, Teodoro Chisesi, Juan Carlos Ruiz, Rina Mariuxi Quinto Briones, Luisa Siculella, Stefano Guzzinati and 3 more

Abstract read
In one paragraph

Article in Cancer reports (Hoboken, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Stefano Nicolas ChisesiAngela Serra Association for Cancer Research, Pierto Baquerizo Moreno, San Cristobal, Galapagos, Ecuador.
Massimo RuggeDepartment of Medicine (DIMED), Surgical Pathology and Cytopathology Unit, University of Padova, Padova, Italy.ORCID 0000-0002-0679-0563
Giulia Raffaella GalliDepartment of Biological and Environmental Sciences and Technologies, University of Salento, Lecce, Italy.
Martina ManniDepartment of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena, Italy.
Veronica Mishell Luzuriaga DelgadoAngela Serra Association for Cancer Research, Pierto Baquerizo Moreno, San Cristobal, Galapagos, Ecuador.
Teodoro ChisesiAngela Serra Association for Cancer Research, Pierto Baquerizo Moreno, San Cristobal, Galapagos, Ecuador.
Juan Carlos RuizUniversity of Specialties Espíritu Santo, Guayaquil, Ecuador.
Rina Mariuxi Quinto BrionesDepartamento de Campaña Preventiva of Guayaquil, Guayaquil, Ecuador.
Luisa SiculellaDepartment of Biological and Environmental Sciences and Technologies, University of Salento, Lecce, Italy.
Stefano GuzzinatiVeneto Cancer Registry, Azienda Zero of the Veneto Region, Padova, Italy.
Manuel ZorziVeneto Cancer Registry, Azienda Zero of the Veneto Region, Padova, Italy.
Massimo FedericoSurgical, Medical and Dental Department of Morphological Sciences Related to Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Anna IannoneSurgical, Medical and Dental Department of Morphological Sciences Related to Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.

Funding

Angela Serra Association for Cancer research, San Cristobal, Avenida Quito y Alsacio Northia, Puerto Baquerizo Moreno, Galapagos, EcuadorAssociation Angela Serra per la ricerca sul cancro-Modena, Italy
6 · The paper itself

Abstract

backgroundCancer incidence in the Galapagos archipelago is unknown.

aimIn 2021, a task force including Ecuadorian and Italian researchers was established to estimate cancer incidence among the 25 244 Galapagos residents.

methodsRegistration covered all malignancies, including malignant melanoma and non-melanoma skin cancers; case recording was based on the International Classification of Diseases for Oncology. The data collection involved an active search across all relevant health institutions on the islands and the mainland. Mortality data were obtained from the Ecuador national mortality registry.

resultsFrom January 2013 and December 2019, 174 new cancer cases were recorded, including 134 malignancies (M:F = 58:76) and 40 non-melanoma skin cancers. The mean age at diagnosis was 48 years for males and 56 years for females. Prostate, gastric, and melanocytic malignancies were most incident among males; breast, thyroid, and cervical cancers prevailed in females. The age-standardized incidence rates (ASR) were 80.39 for males and 99.24 for females with a mortality-to-incidence ratio 0.43. These ASRs were significantly lower than those reported in continental Ecuador and other South American countries.

conclusionsThis pilot cancer registration initiative in the Galapagos record a low incidence of malignancies and requires validation with temporal expansion of cancer registration. The environmental etiology of some of the most common cancers warrants strategic primary and secondary prevention efforts.

Indexed as

NeoplasmsRegistriesAdolescentAdultAgedAged, 80 and overChildChild, PreschoolEcuadorFemaleHumansIncidenceInfantInfant, NewbornMaleMelanomacancer incidencecancer registrationcancer registryGalapagos Islands

Identifiers

PMID39724517
PMCPMC11670741

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.