Evidence map›Paper›PMID 39724419›Full record

ReviewPediatric nephrology (Berlin, Germany)2025

Childhood idiopathic nephrotic syndrome: recent advancements shaping future guidelines.

Eugene Yu-Hin Chan, Olivia Boyer

Abstract readReview
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Nephrotic Syndrome: Current Management.Indian journal of pediatrics · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Eugene Yu-Hin ChanDepartment of Paediatrics, Faculty of Medicine, Chinese University of Hong Kong, Shatin, Hong Kong SAR. eugene.chan@cuhk.edu.hk.ORCID http://orcid.org/0000-0002-1463-6005
Olivia BoyerNéphrologie Pédiatrique, Centre de Référence du Syndrome Néphrotique Idiopathique de L'enfant Et L'adulte, Hôpital Necker - Enfants Malades, APHP, Inserm U1163, Institut Imagine, Université Paris Cité, Paris, France.ORCID http://orcid.org/0000-0002-3957-1359

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Childhood idiopathic nephrotic syndrome is an important pediatric kidney disease associated with significant morbidities and even mortality. Several guidelines have been developed to standardize the terminology and patient care among the pediatric nephrology community. Since the publication of these guidelines, there have been major breakthroughs in the disease management and the understanding of underlying pathogenesis through multi-omics investigations, including the identification of anti-nephrin autoantibodies, genetic susceptibility loci, and the pathogenic role of B cell subsets. In this educational review, we summarize the recent major advancements in idiopathic nephrotic syndrome and attempt to provide potential therapeutic approaches in both steroid-sensitive and steroid-resistant nephrotic syndrome that may shape future guideline development.

Indexed as

NephrologyNephrotic SyndromePractice Guidelines as TopicChildDrug ResistanceGenetic Predisposition to DiseaseHumansMembrane ProteinsPediatricsMembrane ProteinsnephrinFSGSMinimal change diseaseMonogenic podocytopathyNephrotic syndromePediatric nephrologyRituximab

Identifiers

PMID39724419
PMCPMC12187818

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.