Evidence map›Paper›PMID 39724389›Full record

ArticleNeuro-oncology2025

Inhibiting glioblastoma stem cells by targeting pyruvate carboxylase: a novel therapeutic strategy with both opportunities and challenges.

Menghua Chen, Guangjing Mu, Yibo Wu, Rolf Bjerkvig, Hongwei Wang, Donghai Wang, Mingzhi Han

Abstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuro-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Menghua ChenJinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan, China.
Guangjing MuJinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan, China.
Yibo WuJinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan, China.
Rolf BjerkvigDepartment of Biomedicine, University of Bergen, Jonas Lies vei 91, Bergen, Norway.
Hongwei WangJinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan, China.
Donghai WangJinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan, China.
Mingzhi HanMedical Integration and Practice Center, Cheeloo College of Medicine, Shandong University, Jinan, China.ORCID 0000-0001-8357-5974

Funding

Department of Science & Technology of Shandong Province SYS202202Natural Science Foundation of China 82103277Shandong Excellent Young Scientists Fund Program 2022HWYQ-035Shandong Provincial Natural Science Foundation ZR2021QH030Special Foundation for Taishan Young Scholars tsqn202211041
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39724389
PMCPMC11812023

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.