Evidence map›Paper›PMID 39723687›Full record

ReviewJournal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG2025

Practical recommendations for therapy and monitoring of mogamulizumab patients in Germany.

Chalid Assaf, Nina Booken, Edgar Dippel, Gabor Dobos, Hans-Theodor Eich, Claus-Detlev Klemke, Christina Mitteldorf, Jan P Nicolay, Sebastian Theurich, Marion Wobser and 1 more

Abstract readReview
In one paragraph

Review in Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Low-dose total skin electron beam therapy in erythrodermic mycosis fungoides and Sézary syndrome: Results From the Prospective S-MISR Study.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Article
  3. Article
  4. Review
  5. Practical recommendations for therapy and monitoring of mogamulizumab patients in Germany.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chalid AssafDepartment of Dermatology and Venereology, Helios Klinikum Krefeld, Krefeld, Germany.ORCID 0000-0002-7898-9432
Nina BookenDepartment of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Edgar DippelDepartment of Dermatology and Venereology, Klinikum Ludwigshafen, Ludwigshafen, Germany.ORCID 0000-0002-4433-2387
Gabor DobosDepartment of Dermatology, Venereology and Allergology, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-2544-7197
Hans-Theodor EichDepartment of Radiation Oncology, Münster University Hospital, Münster, Germany.
Claus-Detlev KlemkeDepartment of Dermatology and Skin Tumor Center, Municipal Hospital Karlsruhe, Academic Teaching Hospital of the University of Freiburg, Freiburg, Germany.
Christina MitteldorfDepartment of Dermatology, Venereology and Allergology, University Medical Center Göttingen, Göttingen, Germany.
Jan P NicolayDepartment of Dermatology, Venereology and Allergology, University Medical Center Mannheim, Mannheim, Germany.
Sebastian TheurichDepartment of Medicine III, University Hospital LMU, Ludwig-Maximilians-Universität München, München, Germany.
Marion WobserDepartment of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany.
Rudolf StadlerDepartment of Dermatology, Venereology, Allergology and Phlebology, Johannes Wesling Clinic, University Hospital of the Ruhr University Bochum, Bochum, Germany.ORCID 0000-0003-2683-6028

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycosis fungoides (MF) and Sézary syndrome (SS) are the most common subtypes of the heterogeneous group of cutaneous T-cell lymphomas (CTCL). With the expansion of the biologic treatment landscape, new treatment options have become available in recent years, most notably the C-C chemokine receptor 4 (CCR4)-directed monoclonal antibody mogamulizumab. Based on the phase III pivotal trial, mogamulizumab is recommended by the German S2k guidelines for the second-line treatment of stage IB and above SS and MF, after at least one prior systemic therapy. Since then, new insights on safety and efficacy of mogamulizumab were generated by post hoc analyses and real-world evidence. A panel of CTCL-experts discussed available literature and own experiences and developed relevant recommendations on the use of mogamulizumab in clinical practice in Germany. The recommendations cover patient criteria, prior therapies, use of mogamulizumab as monotherapy or combination therapy, management of side effects, duration of therapy, and monitoring schedules. The aim of these clinical recommendations is to support healthcare professionals in their decision-making and use of mogamulizumab in daily practice.

Indexed as

Antibodies, Monoclonal, HumanizedDrug MonitoringMycosis FungoidesSezary SyndromeSkin NeoplasmsGermanyHumansAntibodies, Monoclonal, Humanizedmogamulizumabcombination therapyCTCLCutaneous T‐cell lymphomadrug‐induced exanthemaMARmogamulizumabmogamulizumab‐associated rashmycosis fungoidesSézary syndrome

Identifiers

PMID39723687
PMCPMC11887012

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.