Evidence map›Paper›PMID 39723328›Full record

ReviewCureus2024

Transcutaneous Electrical Nerve Stimulation for Prevention and Treatment of Post-Herpetic Neuralgia: A Narrative Review.

Alan D Kaye, Rahib K Islam, Victoria T Tong, Brynne E Tynes, Kelly R Sala, Brennan Abbott, Chandni R Patel, Isabella B Lentz, Raju Behara, Shilpadevi Patil and 3 more

Abstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alan D KayeDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Rahib K IslamSchool of Medicine, Louisiana State University School of Medicine, New Orleans, USA.
Victoria T TongSchool of Medicine, Louisiana State University (LSU) Health Sciences Center New Orleans School of Medicine, New Orleans, USA.
Brynne E TynesSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.
Kelly R SalaSchool of Medicine, Louisiana Health Sciences Center New Orleans School of Medicine, New Orleans, USA.
Brennan AbbottSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.
Chandni R PatelSchool of Medicine, St. George's University, True Blue, GRD.
Isabella B LentzSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.
Raju BeharaDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Shilpadevi PatilDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Uzayr WasifDepartment of Biology, The State University of New Jersey, New Brunswick, USA.
Sahar ShekoohiDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Giustino VarrassiDepartment of Pain Medicine, Fondazione Paolo Procacci, Rome, ITA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present investigation evaluated transcutaneous electrical nerve stimulation (TENS) for the non-pharmacological treatment of post-herpetic neuralgia (PHN). PHN is the most common complication of the Herpes Zoster virus, affecting one in every five patients with shingles, and presents as intense neuropathic pain that can persist for 90 days or longer after the initial onset of symptoms. Current pharmacological treatment options are mainly limited to symptom management, including oral medications such as tricyclic antidepressants and gabapentinoid preparations, as well as topical options such as lidocaine or capsaicin. TENS is a minimally invasive, non-pharmacological electrical nerve stimulation device currently approved for the treatment of neuropathic pain in adults, providing patients with an alternative or adjunct treatment option to medication with a reduced potential for unwanted side effects, drug-drug interactions or potentially life-threatening toxicity. Current indications for the use of TENS in the treatment of PHN are recommended only after therapeutic goals are attempted and unsuccessfully met by current mainstay medications. More research into the efficacy and safety of TENS for treating PHN should be conducted to clarify further its role as a mainstay treatment for this condition.

Indexed as

electrical nerve stimulationneuropathic painpost herpetic neuralgiashinglestranscutaneous

Identifiers

PMID39723328
PMCPMC11669350

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.