Evidence map›Paper›PMID 39723267›Full record

ArticleCureus2024

Clinical Impact and Significant Technical Points of Transarterial Chemoembolization (TACE) Using the Smaller Drug-Eluting Bead M1 (DC Bead M1™) for Hepatocellular Carcinoma: A Case Series.

Yusuke Kawamura, Norio Akuta, Shigeki Yamamoto, Yasuka Eriksson, Tetsuya Hosaka, Satoshi Saitoh, Hitomi Sezaki, Fumitaka Suzuki, Kenji Ikeda, Hiromitsu Kumada

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yusuke KawamuraHepatology, Toranomon Hospital, Tokyo, JPN.
Norio AkutaHepatology, Toranomon Hospital, Tokyo, JPN.
Shigeki YamamotoHepatology, Toranomon Hospital, Tokyo, JPN.
Yasuka ErikssonHepatology, Toranomon Hospital, Tokyo, JPN.
Tetsuya HosakaHepatology, Toranomon Hospital, Tokyo, JPN.
Satoshi SaitohHepatology, Toranomon Hospital, Tokyo, JPN.
Hitomi SezakiHepatology, Toranomon Hospital, Tokyo, JPN.
Fumitaka SuzukiHepatology, Toranomon Hospital, Tokyo, JPN.
Kenji IkedaHepatology, Toranomon Hospital, Tokyo, JPN.
Hiromitsu KumadaHepatology, Toranomon Hospital, Tokyo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis case series evaluated the clinical impact and significant technical points of transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) using the smaller drug-eluting bead (DEB) M1 (DC Bead M1

methodsWe evaluated 12 patients and 14 HCC nodules treated with DEB-TACE using the DC Bead M1

resultsNine HCC nodules (64%) showed a complete response by modified Response Evaluation Criteria in Solid Tumors (mRECIST), while two nodules (14%) had a partial response. Finally, 11 nodules (79%) showed an objective response (OR). Moreover, IVR-CT showed target nodules with retention of homogeneous contrast medium after DEM1-TACE, eight of nine (89%) nodules achieved a complete response and nine of nine (100%) nodules showed an OR, resulting in an objective response rate (ORR) of 100%. In contrast, in nodules without retention of homogeneous contrast medium in treated target nodules after DEM1-TACE, two of five (40%) nodules showed OR, resulting in an ORR of 40%. The ORR was significantly higher in the group with retention of homogeneous contrast medium after DEM1-TACE (

conclusionsDEM1-TACE had good treatment responses in patients with HCC. Evaluating retention of homogeneous contrast medium after DEM1-TACE using IVR-CT is one of the main predictors of treatment success.

Indexed as

advanced hepatocellular carcinomadc bead m1deb-tacedem1-tacedrug-eluting beadepirubicinsystemic therapy

Identifiers

PMID39723267
PMCPMC11669395

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.