Evidence map›Paper›PMID 39722803›Full record

ArticleFrontiers in endocrinology2024

Negative correlation between cardiometabolic index and testosterone in male adults.

Jing Xu, Yue-Chun Li

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jing XuDepartment of Endocrinology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Yue-Chun LiDepartment of Cardiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Insulin resistance (IR) is closely correlated with a deficiency or decrease of testosterone levels in males. Cardiometabolic index (CMI) is correlated with various diseases correlated with IR. The primary objective of this study is to explore the correlation between CMI and testosterone levels in male adults. Methods: Data from the National Health and Nutrition Examination Survey (NHANES) during the period from 2013 to 2020 were analyzed through a cross-sectional design. CMI was calculated by multiplying waist-to-height ratio (WHtR) with the triglyceride-to-high-density lipoprotein cholesterol ratio (TG/HDL-C). Results: A total of 5012 subjects were included in the final analysis. After controlling confounding variables, multiple linear regression analysis indicated an independent negative correlation between CMI and testosterone levels (β= -6.40, 95% CI: -8.95, -3.86, P<0.001) through the. In addition, a negative non-linear correlation was also found between CMI and testosterone (P<0.05), with CMI's inflection point as 0.73. Subgroup analyses indicated a more significant negative correlation among those with normal weight and the elderly ( Conclusion: Elevated CMI is significantly and negatively correlated with testosterone in male adults.

Indexed as

TestosteroneAdultAgedCardiometabolic Risk FactorsCardiovascular DiseasesCholesterol, HDLCross-Sectional StudiesHumansInsulin ResistanceMaleMiddle AgedNutrition SurveysTriglyceridesYoung AdultCholesterol, HDLTestosteroneTriglyceridescardiometabolic indexdiabetes mellitusinsulin resistanceobesitytestosterone deficiency

Identifiers

PMID39722803
PMCPMC11668973

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.