Evidence map›Paper›PMID 39722590›Full record

ArticleGut microbes2025

Gut microbes with the

Wei-Kai Wu, Yi-Ling Lo, Jian-Ying Chiu, Chia-Lang Hsu, I-Hsuan Lo, Suraphan Panyod, Yu-Chieh Liao, Tina H T Chiu, Yu-Tang Yang, Han-Chun Kuo and 11 more

Erratum issued Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05980884 (Evaluation of Microbial-derived TMAO Production From Carnitine Intake by Testing Fecal Gbu Gene), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05980884 naactive not recruitingnot on this map

Evaluation of Microbial-derived TMAO Production From Carnitine Intake by Testing Fecal Gbu Gene

TypeinterventionalSponsorNational Taiwan University HospitalRan2023 to 2026Enrolled230ConditionsGut Dysbiosis for TMAO Production From L-carnitine ConsumptionArmsL-carnitine
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Gut microbes · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Advancing Precision Nutrition Through Multimodal Data and Artificial Intelligence.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  6. Article
  7. Trimethylamine-Annals of medicine · 2025
    Review
  8. Review
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Wei-Kai WuBachelor Program of Biotechnology and Food Nutrition, National Taiwan University, Taipei, Taiwan.ORCID 0000-0002-9476-8998
Yi-Ling LoR&D Department, Leeuwenhoek Laboratories Co. Ltd, Taipei, Taiwan.
Jian-Ying ChiuDepartment of Medical Research, National Taiwan University Hospital, Taipei, Taiwan.
Chia-Lang HsuDepartment of Medical Research, National Taiwan University Hospital, Taipei, Taiwan.
I-Hsuan LoDepartment of Medical Research, National Taiwan University Hospital, Taipei, Taiwan.
Suraphan PanyodInstitute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan.
Yu-Chieh LiaoNational Center for Geriatrics and Welfare Research, National Health Research Institutes, Yunlin, Taiwan.
Tina H T ChiuNational Laboratory Animal Center, National Applied Research Laboratories, Taipei, Taiwan.
Yu-Tang YangInstitute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan.
Han-Chun KuoGraduate Institute of Microbiology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Hsin-Bai ZouInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Yi-Hsun ChenInstitute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan.
Hsiao-Li ChuangSchool of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan.
Jeffrey J Y YenR&D Department, Leeuwenhoek Laboratories Co. Ltd, Taipei, Taiwan.
Jin-Town WangDepartment of Chemistry, National Taiwan University, Taipei, Taiwan.
Han-Mo ChiuDepartment of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Cheng-Chih HsuGraduate Institute of Oncology, National Taiwan University, Taipei, Taiwan.
Ching-Hua KuoGraduate Institute of Microbiology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Lee-Yan SheenInstitute of Food Science and Technology, National Taiwan University, Taipei, Taiwan.
Hsien-Li KaoDepartment of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Ming-Shiang WuDepartment of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut microbial metabolism of L-carnitine, which leads to the production of detrimental trimethylamine N-oxide (TMAO), offers a plausible link between red meat consumption and cardiovascular risks. Several microbial genes, including

Indexed as

BacteriaBiomarkersCarnitineFecesGastrointestinal MicrobiomeMethylaminesAdultAnimalsFemaleHumansMaleMetagenomicsMiceMiddle AgedMultigene FamilyPrecision MedicineBiomarkersCarnitineMethylaminestrimethyloxaminegbu gene clusterGut microbiomeL-carnitinePersonalized nutritionRed meatTrimethylamine N-oxide

Identifiers

PMID39722590
PMCPMC12026204

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.