Evidence map›Paper›PMID 39722582›Full record

ReviewTherapeutic delivery2025

Iron oxide nanoparticles: a versatile nanoplatform for the treatment and diagnosis of ovarian cancer.

Neelam Poonia, Vipan Kumar, Rudra Narayan Subudhi, Manoj Dalabehera, Anupama Setia, Kundan Singh Bora, Vimal Arora

Abstract readReview
In one paragraph

Review in Therapeutic delivery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Neelam PooniaDepartment of Pharmaceutics, University Institute of Pharma Sciences, Chandigarh University, Mohali, India.
Vipan KumarDepartment of Pharmaceutical Chemistry, Swami Vivekanand College of Pharmacy, Rajpura, India.
Rudra Narayan SubudhiUniversity Institute of Pharma Sciences, Chandigarh University, Mohali, India.
Manoj DalabeheraUniversity Institute of Pharma Sciences, Chandigarh University, Mohali, India.
Anupama SetiaDepartment of Pharmaceutics, JCDM College of Pharmacy, Sirsa, India.
Kundan Singh BoraDepartment of Pharmacognosy, University Institute of Pharma Sciences, Chandigarh University, Mohali, India.
Vimal AroraDepartment of Pharmaceutics, University Institute of Pharma Sciences, Chandigarh University, Mohali, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian cancer remains one of the main causes of human mortality, accounting for millions of deaths every year. Despite of several clinical options such as chemotherapy, photodynamic therapy (PDT), hormonal treatment, radiation therapy, and surgery to manage this disease, the mortality rate is still very high. This alarming statistic highlights the urgent need for innovative approaches to improve both diagnosis and treatment. Success stories of iron oxide nanoparticles, i.e. Ferucarbotran (Resovist®) and Ferrixan (Cliavist®) for liver imaging, CNS (Central nervous system) imaging, cell labeling, etc. have motivated researchers to explore these nanocarriers for treatment and diagnosis of different diseases. Iron oxide nanoparticles have improved the therapeutic efficacy of anticancer drugs through targeted delivery, heat/ROS (reactive oxygen species) generation on application of external energy and have also shown great potential as contrast agents for magnetic resonance imaging (MRI). Their unique magnetic properties enable sensitive imaging, and surface modification allows the attachment of specific biomolecules for targeted detection of ovarian cancer cells. Their unique properties,

Indexed as

Antineoplastic AgentsFerric CompoundsMagnetic Iron Oxide NanoparticlesOvarian NeoplasmsAnimalsContrast MediaDrug Delivery SystemsFemaleHumansMagnetic Resonance ImagingAntineoplastic AgentsContrast MediaFerric Compoundsdiagnosticsdrug deliveryIron oxide nanoparticlesovarian cancerstimuli-responsivenesstheranostics

Identifiers

PMID39722582
PMCPMC11970791

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.