Evidence map›Paper›PMID 39722561›Full record

SynthesisImmunity, inflammation and disease2024

Phenotypic and Allelic Frequencies of ABO and Rh(D) Blood Antigens in Ghana: A Systematic Review.

Charles Nkansah, Felix Osei-Boakye, Samuel K Appiah, Gabriel Abbam, Moses Banyeh, Samira Daud, Richard V Duneeh, Simon B Bani, Boniface N Ukwah, Charles A Derigubah and 3 more

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Immunity, inflammation and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Charles NkansahDepartment of Haematology, School of Allied Health Sciences, University for Development Studies, Tamale, Ghana.ORCID 0000-0001-6986-9976
Felix Osei-BoakyeDepartment of Medical Laboratory Science, Faculty of Health Sciences and Technology, Ebonyi State University, Abakaliki, Nigeria.ORCID 0000-0001-5126-7424
Samuel K AppiahDepartment of Haematology, School of Allied Health Sciences, University for Development Studies, Tamale, Ghana.ORCID 0000-0003-1855-5840
Gabriel AbbamDepartment of Haematology, School of Allied Health Sciences, University for Development Studies, Tamale, Ghana.
Moses BanyehDepartment of Biomedical Laboratory Sciences, School of Allied Health Sciences, University for Development Studies, Tamale, Ghana.ORCID 0000-0003-3594-6077
Samira DaudDepartment of Haematology, School of Allied Health Sciences, University for Development Studies, Tamale, Ghana.
Richard V DuneehDepartment of Medical Laboratory Science, School of Allied Health Sciences, University of Health and Allied Sciences, Ho, Ghana.
Simon B BaniDepartment of Biomedical Laboratory Sciences, School of Allied Health Sciences, University for Development Studies, Tamale, Ghana.
Boniface N UkwahDepartment of Medical Laboratory Science, Faculty of Health Sciences and Technology, Ebonyi State University, Abakaliki, Nigeria.
Charles A DerigubahDepartment of Medical Laboratory Science, Faculty of Health Sciences and Technology, Ebonyi State University, Abakaliki, Nigeria.
Victor U UsangaDepartment of Medical Laboratory Science, Faculty of Health Sciences and Technology, Ebonyi State University, Abakaliki, Nigeria.
Emmanuel Appiah-KubiDepartment of Biomedical Laboratory Sciences, School of Allied Health Sciences, University for Development Studies, Tamale, Ghana.
Ejike F ChukwurahDepartment of Medical Laboratory Science, Faculty of Health Sciences and Technology, Ebonyi State University, Abakaliki, Nigeria.

Funding

The authors received no specific funding for this work.
6 · The paper itself

Abstract

backgroundABO and Rh blood group systems are the most significant blood group systems recognized by the International Society of Blood Transfusion and are widely used for clinical and anthropological purposes. This systematic review determined the distribution and allelic frequency of ABO and Rh(D) antigens in Ghana.

methodsLiterature searches were performed in PubMed, Google Scholar, Web of Science, and ScienceDirect, up to February 20, 2024, and included studies published from 2000 to 2024 in all regions of Ghana. The search terms used to retrieve the preferred literature were "Blood Group/Antigen" and "ABO and Rh(D)" and "Distribution/Frequency/Prevalence," coupled with the names of the different regions/districts/municipalities in Ghana. Similar blood group individuals from all the regions were added, and countrywide data were gathered. The Hardy-Weinberg model was used to estimate the allelic frequency of blood antigens.

resultsBlood group O (54.72%) was the predominant group in the Ghanaian population, followed by B (21.74%), A (19.65%), and AB (3.89%). Rh(D) antigen was present in 92.28% of the population, and only 7.72% were Rh(D) negative. The calculated allelic frequencies of A, B, O, Rh(D) positive, and Rh(D) negative were 0.1227, 0.1376, 0.7397, 0.7222, and 0.2778 for I

conclusionThe phenotypic frequency of the ABO blood group occurred in the pattern O>B>A>AB, and the prevalence of the Rh(D) negative blood group was 7.72% in Ghana. Future nationwide studies are recommended to assess the distribution of ABO, Rh, and other blood group systems.

Indexed as

ABO Blood-Group SystemGene FrequencyPhenotypeRh-Hr Blood-Group SystemAllelesGhanaHumansABO Blood-Group SystemRh-Hr Blood-Group SystemABO blood groupallelic frequencyGhanaian populationRh(D) blood group

Identifiers

PMID39722561
PMCPMC11669777

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.