Evidence map›Paper›PMID 39722214›Full record

ArticleInfluenza and other respiratory viruses2024

The National Burden of Influenza-Associated Respiratory Illness Across Levels of Severity in Egypt, 2016-2019.

Manal Fahim, Ola Deghedy, Walaa Alim, Reham Kamel, Hossam Hassan, Amira Mohsen, Rania Attia, Hala Abou El Naja, Salma Afifi, Stefano Tempia and 1 more

Abstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Manal FahimPreventive Sector, Ministry of Health and Population, Cairo, Egypt.ORCID 0000-0002-7206-4818
Ola DeghedyPreventive Sector, Ministry of Health and Population, Cairo, Egypt.ORCID 0000-0001-5022-5484
Walaa AlimPreventive Sector, Ministry of Health and Population, Cairo, Egypt.ORCID 0000-0002-5059-1473
Reham KamelPreventive Sector, Ministry of Health and Population, Cairo, Egypt.ORCID 0000-0001-6973-2662
Hossam HassanEgypt Country Office, World Health Organization, Cairo, Egypt.
Amira MohsenEgypt Country Office, World Health Organization, Cairo, Egypt.
Rania AttiaEastern Mediterranean Regional Office, World Health Organization, Cairo, Egypt.ORCID 0000-0003-1441-6181
Hala Abou El NajaEastern Mediterranean Regional Office, World Health Organization, Cairo, Egypt.
Salma AfifiMinistry of Health and Population, Cairo, Egypt.
Stefano TempiaGlobal Influenza Program, World Health Organization, Geneva, Switzerland.ORCID 0000-0003-4395-347X
Amr KandeelMinistry of Health and Population, Cairo, Egypt.

Funding

World Health Organization 001
6 · The paper itself

Abstract

introductionInfluenza burden (IB) estimates are crucial for monitoring disease trends, allocating limited resources, and promoting influenza vaccination. However, IB in Egypt is poorly understood. This study estimates the mean-seasonal IB in Egypt, across levels of severity by age and regions using sentinel surveillance data between 2016 and 2019.

methodsInfluenza surveillance was implemented among patients hospitalized with severe acute respiratory infection (SARI) at eight sentinel hospitals across Egypt. We estimated the influenza-associated SARI hospitalization in two governorates and then extrapolated nationally using the World Health Organization (WHO)-recommended methods. Thereafter, we estimated IB-associated mild/moderate illness and deaths using IB pyramid tool developed by WHO and the John Hopkins Center for Health Security. Rates were reported per 100,000 population.

resultsThe estimated mean seasonal number of influenza-associated mild/moderate illness, hospitalized noncritically and critically ill patients, and deaths was 16,425,938 (95% CI: 1,150,888-40,409,614), 30,335 (95% CI: 9971-670,288), 9110 (95% CI: 580-16,321), and 2660 (95% CI: 154-9908), respectively. The highest rate of influenza-associated mild/moderate illness was among aged 5-14 year (22,932; 95% CI: 825-25,546.3), whereas the highest rates of severe influenza were among aged > 65 years (hospitalizations: 159.4, 95% CI: 121.7-205.0; deaths: 56.0, 95% CI: 0.6-111.0). Children aged < 5 years also experience high rates of influenza-associated hospitalization (52.0, 95% CI: 43.0-62.0).

conclusionsThe WHO method estimated a high burden of severe influenza among aged ≥ 65 and aged < 5 years in Egypt. To reduce severe IB, increased influenza vaccine uptake together with enhanced immunization strategies implementations among the elderly and children are warranted.

Indexed as

Cost of IllnessHospitalizationInfluenza, HumanSentinel SurveillanceAdolescentAdultAgedAged, 80 and overChildChild, PreschoolEgyptFemaleHumansInfantMaleMiddle Agedburdeninfluenza virussevere acute respiratory infectionsurveillance

Identifiers

PMID39722214
PMCPMC11669627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.