ArticleThe Veterinary record2024
Urinary protein-to-creatinine ratio in guinea pigs (Cavia porcellus): Reference range and the effect of age and sex.
Article in The Veterinary record, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Exploratory Study of the Urine Protein-to-Creatinine Ratio in Apparently Healthy Horses.Veterinary sciences · 2025Article
- Urinary protein-to-creatinine ratio in guinea pigs (Cavia porcellus): Reference range and the effect of age and sex.The Veterinary record · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundThere are currently few reports on the normal urinary protein-to-creatinine (UPC) ratio of guinea pigs, and there is little information on the effects of age and sex on this parameter.
methodsUrinary protein and creatinine concentrations were measured in a total of 161 clinically healthy guinea pigs, and the UPC ratio was subsequently calculated. The effect of age and sex on these parameters was assessed using Mann-Whitney U tests. Using these data, UPC ratio reference ranges were established.
resultsGuinea pig pups younger than 6 months had a significantly higher UPC ratio than adult animals (median UPCs of 1.48 and 0.56, respectively). There was no effect of sex on this parameter. The reference range for the UPC ratio in adult guinea pigs was set at 0.12-2.21. For guinea pigs younger than 6 months, the reference range for the UPC ratio was set at 0.4-3.1. LIMITATIONS: This study was limited by the lack of blood analysis, which could reveal a subclinical health problem that could affect renal function and the extent of proteinuria.
conclusionIn guinea pigs, the UPC ratio is influenced by age but not by sex. Therefore, the reference range established for adult guinea pigs cannot be used for pups younger than 6 months.
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