Evidence map›Paper›PMID 39722143›Full record

ArticleClinical endoscopy2025

Efficacy and safety of endoscopic ultrasound-guided hepaticogastrostomy for biliary drainage in hypervascular hepatocellular carcinoma: a retrospective study from Japan.

Kenneth Tachi, Kazuo Hara, Nozomi Okuno, Shin Haba, Takamichi Kuwahara, Toshitaka Fukui, Ahmed Mohammed Sadek, Hossam El-Din Shaaban Mahmoud Ibrahim, Minako Urata, Takashi Kondo and 1 more

Abstract read
In one paragraph

Article in Clinical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kenneth TachiDepartment of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan.
Kazuo HaraDepartment of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan.
Nozomi OkunoDepartment of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan.
Shin HabaDepartment of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan.
Takamichi KuwaharaDepartment of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan.
Toshitaka FukuiDepartment of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan.
Ahmed Mohammed SadekDepartment of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan.
Hossam El-Din Shaaban Mahmoud IbrahimDepartment of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan.
Minako UrataDepartment of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan.
Takashi KondoDepartment of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan.
Yoshitaro YamamotoDepartment of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsBiliary obstruction drainage in patients with hepatocellular carcinoma (HCC) is associated with symptom palliation, improved access to chemotherapy, and improved survival. Stent placement and exchange via endoscopic retrograde cholangiopancreatography biliary drainage risk traversing the HCC, a hypervascular tumor and causing bleeding. Endoscopic ultrasound-guided hepaticogastrostomy (EUS-HGS) potentially prevents procedure-related bleeding. Therefore, we evaluated the efficacy and safety of EUS-HGS as an alternative treatment for biliary obstruction in patients with HCC.

methodsThis was a retrospective study of all EUS-HGS procedures performed in patients with HCC at the Aichi Cancer Center Hospital, Japan, from February 2017 to August 2023.

resultsA total of 14 EUS-HGS procedures (42.9% primary) were attempted in 10 HCC patients (mean age 71.5 years, 80.0% male). Clinical and technical success rates were 92.9% and 90.9%, respectively. The observed procedure details in the 13 successful procedures included B3 puncture (53.8%), 22-G needle (53.8%), fully covered self-expandable metal stent (100%), and mean procedure time (32.7 minutes). There was no bleeding. Mild complications occurred in 27.3%. All patients resumed oral intake within 24 hours.

conclusionsEUS-HGS is a technically feasible and clinically effective initial or salvage drainage option for the treatment of biliary obstruction in patients with HCC.

Indexed as

CholangitisEndosonographyFibrosisHepatocellular carcinomaObstructive jaundice

Identifiers

PMID39722143
PMCPMC12138352

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.