ArticleBMC public health2024
Outbreak of cholera in the Southwest region of Cameroon, 2021-22: an epidemiological investigation.
Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Effect of Supervision or Short Messages (SMS) on the Detection Rate of Diseases Under Surveillance in the Littoral Region of Cameroon: A Randomized Controlled Health Facility-Based Trial.Research and reports in tropical medicine · 2026Article
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13 authors.
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Abstract
backgroundIn October 2021, a large outbreak of cholera was declared in Cameroon, disproportionately affecting the Southwest region, one of 10 administrative regions in the country. In this region, the cases were concentrated in three major cities where a humanitarian crisis had concomitantly led to an influx of internally displaced persons. Meanwhile, across the border, Nigeria was facing an unprecedented cholera outbreak. In this paper, we describe the spread of cholera in the region and analyse associated factors.
methodsWe analysed surveillance data collected in the form of a line list between October 2021 and July 2022. In a case-control study, we assessed factors associated with cholera, with specific interest in the association between overcrowding (defined by the number of household members) and cholera.
resultsBetween October 15, 2021 and July 21, 2022, 6,023 cases (median age 27 years, IQR 18-40, 54% male) and 93 deaths (case fatality 1.54%) were recorded in the region. In total 5,344 (89%) cases were reported from 6 mainland health districts (attack rate 0.47%), 679 (11%) from 4 maritime health districts (attack rate 0.32%). More than 80% of cases were recorded in 3 of 10 health districts: Limbe, Buea, and Tiko. The first cases originated from maritime health districts along the Nigeria-Cameroon border, and spread progressively in-country over time, with an exponential rise in number of cases in mainland health districts following pipe-borne water interruptions. Case fatality was higher in maritime health districts (3.39%) compared to mainland districts (1.5%, p < 0.01). We did not find an association between overcrowding and cholera, but the results suggest a potential dose-response relationship with an increasing number of household members (>5 people: (crude OR 1.73, 95% CI 0.97-3.12) and 3-5 people: (crude OR 1.47, 95% CI 0.85-2.60)), even after adjusting for internally displaced status and number of household compartments in the multivariable model (aOR 1.54, 95% CI 0.80-3.02).
conclusionsWe report the largest cholera outbreak in the Southwest region. Our findings suggest the cross-border spread of cases from the Nigerian outbreak, likely driven by overcrowding in major cities. Our study highlights the need for cross-border surveillance, especially during humanitarian crises.
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