Evidence map›Paper›PMID 39722004›Full record

ArticleBMC cancer2024

A distinct subgroup of AML resembling the APL immunophenotype is associated with DIC.

Pan Li, Li Liu, Fuling Zhou

Abstract read
In one paragraph

Article in BMC cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. APL-like subset withinHemaSphere · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pan LiDepartment of Hematology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Li LiuDepartment of Hematology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Fuling ZhouDepartment of Hematology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. zhoufuling@whu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe complexity of acute myeloid leukemia (AML) is increasingly recognized through the identification of distinct subgroups, including those with an APL-like immunophenotype characterized by the absence of CD34 and HLA-DR expression, which is widely recognized as a representative immunophenotype in acute promyelocytic leukemia (APL). This study sought to understand the clinical, molecular, and prognostic differences between AML patients with and without this phenotype.

methodsThis study retrospectively analysed 191 de novo non-M3 AML patients and identified 32 patients with the CD34

resultsPatients with the CD34 DISCUSSION: The findings highlight the patients exhibiting the CD34

Indexed as

Disseminated Intravascular CoagulationImmunophenotypingLeukemia, Myeloid, AcuteLeukemia, Promyelocytic, AcuteNucleophosminAdolescentAdultAgedAged, 80 and overAntigens, CD34FemaleHLA-DR AntigensHumansMaleMiddle AgedPrognosisAntigens, CD34HLA-DR AntigensNPM1 protein, humanNucleophosminAMLCD34−HLA-DR− phenotypeDICImmunophenotypeNPM1

Identifiers

PMID39722004
PMCPMC11670352

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.