Evidence map›Paper›PMID 39721961›Full record

ArticleBJPsych open2024

Lost and found: dynamics of relationship and employment status over time in people with affective and psychotic spectrum disorders.

Fanny Senner, Lisa Kerkhoff, Kristina Adorjan, Michael Lauseker, Monika Budde, Maria Heilbronner, Janos L Kalman, Mojtaba Oraki Kohshour, Sergi Papiol, Daniela Reich-Erkelenz and 25 more

Abstract read
In one paragraph

Article in BJPsych open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. BJPsych open · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Fanny SennerInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Germany.ORCID https://orcid.org/0000-0003-3375-5314
Lisa KerkhoffInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Germany.
Kristina AdorjanInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Germany.ORCID https://orcid.org/0000-0001-7501-9556
Michael LausekerInstitute for Medical Information Processing, Biometry, and Epidemiology, Faculty of Medicine, LMU Munich, Germany.
Monika BuddeInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Germany.
Maria HeilbronnerInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Germany.
Janos L KalmanInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Germany.ORCID https://orcid.org/0000-0003-0930-4214
Mojtaba Oraki KohshourInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Germany.ORCID https://orcid.org/0000-0002-1357-2636
Sergi PapiolInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Germany.
Daniela Reich-ErkelenzInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Germany.
Sabrina K SchauppInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Germany.
Eva C SchulteInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Germany.ORCID https://orcid.org/0000-0003-3105-5672
Thomas VoglInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Germany.
Ion-George AnghelescuDepartment of Psychiatry and Psychotherapy, Mental Health Institute Berlin, Germany.
Volker AroltInstitute for Translational Psychiatry, University of Münster, Germany.
Bernhardt T BauneDepartment of Psychiatry, University of Münster, Germany.
Udo DannlowskiInstitute for Translational Psychiatry, University of Münster, Germany.
Nina DalknerDivision of Psychiatry and Psychotherapeutic Medicine, Research Unit for Bipolar Affective Disorder, Medical University of Graz, Austria.
Detlef E DietrichAMEOS Clinical Center Hildesheim, Hildesheim, Germany.
Andreas J FallgatterDepartment of Psychiatry and Psychotherapy, Tübingen Center for Mental Health (TüCMH), University of Tübingen, Germany.
Christian FiggeKarl-Jaspers Clinic, European Medical School Oldenburg-Groningen, Oldenburg, Germany.
Carsten KonradDepartment of Psychiatry and Psychotherapy, Agaplesion Diakonieklinikum, Rotenburg, Germany.
Fabian U LangDepartment of Psychiatry II, Ulm University, Bezirkskrankenhaus Günzburg, Günzburg, Germany.
Jens ReimerDepartment of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Eva Z ReinighausDivision of Psychiatry and Psychotherapeutic Medicine, Research Unit for Bipolar Affective Disorder, Medical University of Graz, Austria.
Max SchmaußDepartment of Psychiatry, Psychotherapy, and Psychosomatics, Faculty of Medicine, University of Augsburg, Germany.
Andrea SchmittDepartment of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Germany.
Simon SennerCenter for Psychiatry Reichenau, Academic Hospital University of Konstanz, Germany.
Carsten SpitzerDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center Rostock, Germany.
Jörg ZimmermannPsychiatrieverbund Oldenburger Land gGmbH, Karl-Jaspers-Klinik, Bad Zwischenahn, Germany.
Alkomiet HasanDepartment of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Peter FalkaiDepartment of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Germany.
Thomas G SchulzeInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Germany.
Urs HeilbronnerInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Germany.
Sophie-Kathrin GreinerDepartment of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Germany.ORCID https://orcid.org/0000-0003-3607-1217

Funding

Bundesministerium für Bildung und Forschung 01EE1404HDeutsche Forschungsgemeinschaft 514201724Deutsche Forschungsgemeinschaft FA241/16-1Deutsche Forschungsgemeinschaft SCHU 1603/4-1, 5-1, 7-1;
6 · The paper itself

Abstract

backgroundEmployment and relationship are crucial for social integration. However, individuals with major psychiatric disorders often face challenges in these domains.

aimsWe investigated employment and relationship status changes among patients across the affective and psychotic spectrum - in comparison with healthy controls, examining whether diagnostic groups or functional levels influence these transitions.

methodThe sample from the longitudinal multicentric PsyCourse Study comprised 1260 patients with affective and psychotic spectrum disorders and 441 controls (mean age ± s.d., 39.91 ± 12.65 years; 48.9% female). Multistate models (Markov) were used to analyse transitions in employment and relationship status, focusing on transition intensities. Analyses contained multiple multistate models adjusted for age, gender, job or partner, diagnostic group and Global Assessment of Functioning (GAF) in different combinations to analyse the impact of the covariates on the hazard ratio of changing employment or relationship status.

resultsThe clinical group had a higher hazard ratio of losing partner (hazard ratio 1.46,

conclusionPatients face an increased hazard of job loss and relationship dissolution compared with healthy controls, and this is partially conditioned by the diagnosis and functional level. These findings underscore a high demand for destigmatisation and support for individuals in managing their functional limitations.

Indexed as

affectivedestigmatisationfunctional levelpsychoticSocial integration

Identifiers

PMID39721961
PMCPMC11733486

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.