Evidence map›Paper›PMID 39721687›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Ulcerative Colitis with Acute Pericarditis after Dose Escalation of Mesalazine.

Jun Wada, Kazumasa Kawashima, Michio Onizawa, Naohiko Gunji, Yu Watahiki, Chiharu Sakuma, Mai Murakami, Tomoaki Mochimaru, Shunsuke Miura, Hiromasa Ohira

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jun WadaDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Japan.
Kazumasa KawashimaDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Japan.
Michio OnizawaDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Japan.
Naohiko GunjiDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Japan.
Yu WatahikiDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Japan.
Chiharu SakumaDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Japan.
Mai MurakamiDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Japan.
Tomoaki MochimaruDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Japan.
Shunsuke MiuraDepartment of Cardiovascular Medicine, Fukushima Medical University, Japan.
Hiromasa OhiraDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesalazine-induced pericarditis is rare, and most cases occur at the time of treatment initiation. A 30-year-old man with ulcerative colitis who had experienced remission for 2 years with mesalazine 2,000 mg/day subsequently experienced relapse. Therefore, the mesalazine dose was increased to 4,000 mg. Thereafter, hematochezia improved, but anterior chest pain developed. Chest radiography revealed marked cardiac dilation (cardiothoracic ratio, 63%) and echocardiography revealed pericardial effusion. Adverse events associated with mesalazine should be carefully monitored, not only at the time of treatment initiation but also after dose escalation.

Indexed as

Anti-Inflammatory Agents, Non-SteroidalColitis, UlcerativeMesalaminePericarditisAcute DiseaseAdultDose-Response Relationship, DrugHumansMaleAnti-Inflammatory Agents, Non-SteroidalMesalaminedose escalationmesalazinepericarditisulcerative colitis

Identifiers

PMID39721687
PMCPMC12331334

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.