Evidence map›Paper›PMID 39721682›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Diffuse Large B-cell Lymphoma with a Multilobated Nuclear Morphology Harboring t(14;18)(q32;q21) and t(3;22)(q27;q11).

Masahiro Manabe, Naoyuki Inano, Yuuji Hagiwara, Ki-Ryang Koh

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Masahiro ManabeDepartment of Hematology, Osaka General Hospital of West Japan Railway Company, Japan.
Naoyuki InanoDepartment of Clinical Laboratory, Osaka General Hospital of West Japan Railway Company, Japan.
Yuuji HagiwaraDepartment of Clinical Laboratory, Osaka General Hospital of West Japan Railway Company, Japan.
Ki-Ryang KohDepartment of Hematology, Osaka General Hospital of West Japan Railway Company, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 70-year-old woman was admitted to our hospital with dyspnea. Atypical cells with multilobated nuclei were observed in the pleural effusion. Diffuse large B-cell lymphoma (DLBCL) was diagnosed based on a cell block analysis. A chromosomal analysis of lymphoma cells revealed t(14;18)(q32;q21) and t(3;22)(q27;q11). The patient's disease was refractory to chemotherapy, and she died within one year. Although flower-like nuclei are typical of adult T-cell lymphoma/leukemia, similar multilobated nuclei may occur in DLBCL. Although multilobated DCBCL have been reported to have a better prognosis than other forms of DLBCL, the abovementioned translocations may have contributed to the patient's aggressive clinical course.

Indexed as

Cell NucleusChromosomes, Human, Pair 14Chromosomes, Human, Pair 18Chromosomes, Human, Pair 22Chromosomes, Human, Pair 3Lymphoma, Large B-Cell, DiffuseTranslocation, GeneticAgedFatal OutcomeFemaleHumanscell blockdiffuse large B-cell lymphomamorphologyt(14;18)(q32;q21)t(3;22)(q27;q11)

Identifiers

PMID39721682
PMCPMC12331281

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.