Evidence map›Paper›PMID 39721680›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Japanese Spotted Fever with Severe Myositis: A Diagnostic Challenge.

Keigo Kobayashi, Haruna Baba, Riki Takeda, Susumu Nishiyama, Shu Nakamoto, Yasuhiro Umekawa

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Keigo KobayashiDepartment of Internal Medicine, Kurashiki Medical Center, Japan.
Haruna BabaCenter for Postgraduate Medical Training, Kurashiki Medical Center, Japan.
Riki TakedaCenter for Postgraduate Medical Training, Kurashiki Medical Center, Japan.
Susumu NishiyamaRheumatic Disease Center, Kurashiki Medical Center, Japan.
Shu NakamotoDepartment of Pathology, Kurashiki Medical Center, Japan.
Yasuhiro UmekawaDepartment of Internal Medicine, Kurashiki Medical Center, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A woman in her late 70s presented with a fever, rashes, and marked proximal muscle weakness. Noninfectious conditions, including myositis and vasculitis, were initially considered. Treatment with cephalosporins was ineffective, but the symptoms improved with minocycline, indicating possible Japanese spotted fever (JSF) despite no apparent history of tick exposure. The diagnosis was confirmed by serological tests. A skin biopsy revealed leukocytoclastic vasculitis with immune complex deposition, suggesting muscle damage due to immune complexes. This case underscores the need to consider JSF in patients with atypical symptoms and initiate timely treatment to prevent severe complications.

Indexed as

MyositisSpotted Fever Group RickettsiosisAgedAnti-Bacterial AgentsFemaleHumansSeverity of Illness IndexAnti-Bacterial Agentsimmune complex depositionJapanese Spotted Fever (JSF)leukocytoclastic vasculitisminocycline treatmentsevere myositis

Identifiers

PMID39721680
PMCPMC12331296

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.