Evidence map›Paper›PMID 39721602›Full record

ArticleACS sensors2025

Pathogen-Specific Electrochemical Real-Time LAMP Detection Using Universal Solid-Phase Probes on Carbon Electrodes.

Martin Trotter, Andreas Schreiber, Dominic Kleinknecht, Zahra Bagherian, Felix von Stetten, Nadine Borst

Abstract read
In one paragraph

Article in ACS sensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Martin TrotterHahn-Schickard, 79110 Freiburg, Germany.ORCID 0000-0002-7495-1939
Andreas SchreiberHahn-Schickard, 79110 Freiburg, Germany.ORCID 0000-0001-8046-1357
Dominic KleinknechtHahn-Schickard, 79110 Freiburg, Germany.ORCID 0009-0004-7801-600X
Zahra BagherianHahn-Schickard, 79110 Freiburg, Germany.ORCID 0000-0002-4652-0760
Felix von StettenHahn-Schickard, 79110 Freiburg, Germany.
Nadine BorstHahn-Schickard, 79110 Freiburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epidemic infections and spreading antibiotic resistance require diagnostic tests that can be rapidly adopted. To reduce the usually time-consuming adaptation of molecular diagnostic tests to changing targets, we propose the novel approach of a repurposable sensing electrode functionalization with a universal, target-independent oligonucleotide probe. In the liquid phase covering the electrode, the target sequence is amplified by MD LAMP (mediator-displacement loop-mediated isothermal amplification) releasing a generic methylene blue-labeled mediator, which specifically hybridizes to the solid-phase probe. To demonstrate the universality of the approach, two different pathogens,

Indexed as

CarbonDNA, BacterialElectrochemical TechniquesMolecular Diagnostic TechniquesNucleic Acid Amplification TechniquesStaphylococcus aureusTreponema pallidumElectrodesHumansLimit of DetectionOligonucleotide ProbesCarbonDNA, BacterialOligonucleotide Probescarbon electrodeDNA testingMRSApoint-of-carereal-time LAMPsignal-onsolid-phase probesuniversal electrochemical detection

Identifiers

PMID39721602
PMCPMC11960684

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.