Evidence map›Paper›PMID 39721557›Full record

ReviewCurrent opinion in neurobiology2025

Release your inhibitions: The cell biology of GABAergic postsynaptic plasticity.

Theresa M Welle, Katharine R Smith

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Ultrafast endocytosis in mouse cortical inhibitory synapses.bioRxiv : the preprint server for biology · 2025
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Theresa M WelleDepartment of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, 12800 East 19th Avenue, Aurora, CO 80045, USA.
Katharine R SmithDepartment of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, 12800 East 19th Avenue, Aurora, CO 80045, USA. Electronic address: katharine.r.smith@cuanschutz.edu.

Funding

Local translation mechanisms to control inhibitory synaptic plasticityR01MH128199 · NIMH · UNIVERSITY OF COLORADO DENVER · PI SMITH, KATHARINE RACHEL · 2022 to 2025
$2.5M
Neuroscience Training GrantT32NS099042 · NINDS · UNIVERSITY OF COLORADO DENVER · PI Nidia Calero, GIDON S FELSEN · 2016 to 2026
$2.1M
Nanoscale organization of the inhibitory synapse during synaptic plasticityR01MH119154 · NIMH · UNIVERSITY OF COLORADO DENVER · PI SMITH, KATHARINE RACHEL · 2020 to 2024
$2.0M
The role of gephyrin translation in inhibitory synaptic plasticityF31NS124108 · NINDS · UNIVERSITY OF COLORADO DENVER · PI WELLE, THERESA MARIE · 2022 to 2024
$93k
NIMH NIH HHS R01 MH119154NIMH NIH HHS R01 MH128199NINDS NIH HHS F31 NS124108NINDS NIH HHS T32 NS099042
6 · The paper itself

Abstract

GABAergic synaptic inhibition controls circuit function by regulating neuronal plasticity, excitability, and firing. To achieve these goals, inhibitory synapses themselves undergo several forms of plasticity via diverse mechanisms, strengthening and weakening phasic inhibition in response to numerous activity-induced stimuli. These mechanisms include changing the number and arrangement of functional GABA

Indexed as

GABAergic Neuronsgamma-Aminobutyric AcidInhibitory Postsynaptic PotentialsNeural InhibitionNeuronal PlasticityReceptors, GABA-ASynapsesAnimalsHumansgamma-Aminobutyric AcidReceptors, GABA-AGABA(A) receptorGephyrinInhibitory synaptic plasticityNanoscale organizationProtein synthesisReceptor traffickingSynaptic inhibition

Identifiers

PMID39721557
PMCPMC11839402

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.