Evidence map›Paper›PMID 39721012›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

The Current Advances in Design Strategy (Indirect Strategy and Direct Strategy) for Type-I Photosensitizers.

Ning Ma, Junjie Wang, Hui Tang, Shiyu Wu, Xiaochun Liu, Kangyao Chen, Yahui Zhang, Xiaoqi Yu

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Spin trap-mediated conversion of singlet oxygen to hydroxyl radical in photosensitization: mechanistic insights and the role of biological reductants.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. A Closed-Loop Hybrid Discovery System of Type I Photosensitizers for Hypoxic Tumor Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ning MaDepartment of Chemistry, School of Science, Xihua University, Chengdu, 610039, China.
Junjie WangDepartment of Chemistry, School of Science, Xihua University, Chengdu, 610039, China.
Hui TangDepartment of Chemistry, School of Science, Xihua University, Chengdu, 610039, China.
Shiyu WuDepartment of Chemistry, School of Science, Xihua University, Chengdu, 610039, China.
Xiaochun LiuDepartment of Chemistry, School of Science, Xihua University, Chengdu, 610039, China.
Kangyao ChenDepartment of Chemistry, School of Science, Xihua University, Chengdu, 610039, China.
Yahui ZhangDepartment of Chemistry, School of Science, Xihua University, Chengdu, 610039, China.ORCID https://orcid.org/0000-0003-1888-2243
Xiaoqi YuDepartment of Chemistry, School of Science, Xihua University, Chengdu, 610039, China.

Funding

Key Research and Development Program of Sichuan ProvinceNational Key R&D Program of China 2023YFB3812400National Key R&D Program of China 2023YFB3812402Sichuan Science and Technology Program 2025 NSFSC2131
6 · The paper itself

Abstract

Type-I photosensitizers (PSs) are among the most potential candidates for photodynamic therapy (PDT), as their low dependence on oxygen endow them with many advantages for treating hypoxic tumor. However, most of the reported type-I PSs have a contingency of molecular design, because electron transfer (ET) reaction is more difficult to achieve than energy transfer (EET) process. Therefore, it is urgent to understand molecular design mechanisms for type-I PSs. In this review, the two ways to achieve the type-I PSs, i.e., inhibiting EET process (type-II) or enhancing ET process (type-I), are detailly explained. In response, the current design strategies of type-I PSs are summarized from two perspectives: indirect strategy (inhibiting EET process: reducing the energy of the lowest triplet excited state (T

Indexed as

Drug DesignPhotochemotherapyPhotosensitizing AgentsElectron TransportEnergy TransferHumansPhotosensitizing Agentsdirect strategyindirect strategyphotodynamic therapytype‐I photosensitizers

Identifiers

PMID39721012
PMCPMC11831511

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.