Evidence map›Paper›PMID 39720904›Full record

ReviewExpert review of medical devices2025

Proactive esophageal cooling during radiofrequency cardiac ablation: data update including applications in very high-power short duration ablation.

Tiffany Sharkoski, Jason Zagrodzky, Nikhil Warrier, Rahul Doshi, Samuel Omotoye, Marcela Mercado Montoya, Tatiana Gómez Bustamante, Enrique Berjano, Ana González Suárez, Erik Kulstad and 1 more

Abstract readReview
In one paragraph

Review in Expert review of medical devices, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tiffany SharkoskiDepartment of Clinical & Medical Affairs, Haemonetics, Boston, MA, USA.
Jason ZagrodzkyCardiac Electrophysiology, St. David's Medical Center, Texas Cardiac Arrhythmia Institute, Austin, TX, USA.
Nikhil WarrierCardiac Electrophysiology, Memorial Care Heart & Vascular Institute, Fountain Valley, CA, USA.
Rahul DoshiCardiac Arrhythmia Group, HonorHealth Medical Group, Scottsdale, AZ, USA.
Samuel OmotoyeCardiac Electrophysiology, Cleveland Clinic, Cleveland, Ohio, USA.
Marcela Mercado MontoyaIN SILICO STEM S.A.S, Medellin, Colombia.
Tatiana Gómez BustamanteIN SILICO STEM S.A.S, Medellin, Colombia.
Enrique BerjanoDepartment of Electronic Engineering, Universitat Politècnica de València, València, Spain.
Ana González SuárezDepartment of Electronic Engineering, Universitat Politècnica de València, València, Spain.
Erik KulstadEmergency Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0002-9331-8266
Mark MetzlCardiac Electrophysiology, NorthShore University Health System, Evanston, IL, USA.

Funding

Utility of Esophageal Cooling Therapy for the Prevention of Thermal Injury During Atrial FibrillationR44HL158375 · NHLBI · ADVANCED COOLING THERAPY, LLC · PI CALLANS, DAVID J, KULSTAD, ERIK BENJAMIN · 2021 to 2023
$3.8M
NHLBI NIH HHS R44 HL158375
6 · The paper itself

Abstract

introductionProactive esophageal cooling reduces injury during radiofrequency (RF) ablation of the left atrium (LA) for the treatment of atrial fibrillation (AF). New catheters are capable of higher wattage settings up to 90 W (very high-power short duration, vHPSD) for 4 s. Varying power and duration, however, does not eliminate the risk of thermal injury. Furthermore, alternative energy sources such as pulsed field ablation (PFA) also exhibit thermal effects, with clinical data showing esophageal temperatures up to 40.3°C. The ensoETM esophageal cooling device (Attune Medical, now a part of Haemonetics, Boston, MA, U.S.A.) is commercially available and FDA-cleared to reduce thermal injury to the esophagus during RF ablation for AF and is recommended in the 2024 expert consensus statement on catheter and surgical ablation of AF. AREAS COVERED: This review summarizes growing evidence of esophageal cooling during high power RF ablation for AF treatment, including data relating to procedural efficacy, safety, and efficiency, and techniques to enhance operator success while providing directions for further research. EXPERT OPINION: Proactive esophageal cooling reduces injury to the esophagus during high power RF ablation, and utilizing this approach may result in increased success in first-pass isolation, procedural efficiency, and long-term efficacy.

Indexed as

Atrial FibrillationCatheter AblationEsophagusHypothermia, InducedRadiofrequency AblationHumansatrial ablationAtrial fibrillationatrioesophageal fistulacatheter ablationesophageal coolingesophageal injuryradiofrequency ablationvery high-power short duration ablation

Identifiers

PMID39720904
PMCPMC11750608

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.