Evidence map›Paper›PMID 39720725›Full record

ArticleFrontiers in immunology2024

Efficient gene deletion of Integrin alpha 4 in primary mouse CD4 T cells using CRISPR RNA pair-mediated fragmentation.

Taeuk Wi, Yurim Choi, Jungsun Kim, Youn Soo Choi, Matthew E Pipkin, Jinyong Choi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Taeuk WiDepartment of Microbiology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Yurim ChoiDepartment of Microbiology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Jungsun KimDepartment of Microbiology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Youn Soo ChoiDepartment of Biomedical Sciences, Department of Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Matthew E PipkinDepartment of Immunology and Microbiology, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, FL, United States.
Jinyong ChoiDepartment of Microbiology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Funding

Transcription factor regulation of CD4 and CD8 T cell effector and memory differentiation and functionP01AI145815 · NIAID · UNIVERSITY OF FLORIDA · PI PIPKIN, MATTHEW EUGENE · 2020 to 2024
$11.0M
NIAID NIH HHS P01 AI145815
6 · The paper itself

Abstract

The functional specialization of CD4 T lymphocytes into various subtypes, including T

Indexed as

CRISPR-Cas SystemsGene DeletionGene EditingIntegrin alpha4AnimalsCD4-Positive T-LymphocytesCell DifferentiationLymphocytic ChoriomeningitisLymphocytic choriomeningitis virusMiceMice, Inbred C57BLRNA, Guide, CRISPR-Cas SystemsTh1 CellsIntegrin alpha4RNA, Guide, CRISPR-Cas SystemsCRISPR-Cas9 gene editingintegrin α4TFHTH1viral infection

Identifiers

PMID39720725
PMCPMC11666438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.