ArticleCureus2024
A Rare Overlap: Sjögren's Syndrome With Autoimmune Hepatitis.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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2 authors.
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Abstract
Sjögren's syndrome (SS) is a chronic autoimmune disorder primarily affecting exocrine glands, leading to symptoms such as dry mouth and dry eyes. While SS can occur as a primary condition, it may overlap with other autoimmune diseases, complicating management. Autoimmune hepatitis (AIH), a liver disorder characterized by elevated serum globulins and liver-specific autoantibodies, can co-occur with SS, although this overlap is rare. We report a case of a 45-year-old woman with primary SS who developed abdominal distension, pedal edema, and abnormal liver function tests, raising suspicion of an overlap syndrome. Autoimmune profiling confirmed primary SS, while liver biopsy indicated AIH and chronic liver disease with portal hypertension. The patient received immunosuppressive therapy, including corticosteroids and azathioprine, along with supportive care for cirrhosis led to stabilization. This case highlights the diagnostic challenges and the need for clinical vigilance in identifying autoimmune overlap syndromes to ensure appropriate management.
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