Evidence map›Paper›PMID 39719952›Full record

ArticleJournal of contemporary brachytherapy2024

A prospective comparison of implant quality between suture-coated seeds and uncoated seeds in prostate cancer brachytherapy.

Makoto Nakiri, Naoyuki Ogasawara, Hirofumi Kurose, Kosuke Ueda, Hiroki Suekane, Katsuaki Chikui, Kiyoaki Nishihara, Keiichiro Uemura, Kazuhisa Ejima, Ryuji Hoshino and 7 more

Abstract read
In one paragraph

Article in Journal of contemporary brachytherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Makoto NakiriDepartment of Urology, Kurume University School of Medicine, Kurume, Japan.
Naoyuki OgasawaraDepartment of Urology, Kurume University School of Medicine, Kurume, Japan.
Hirofumi KuroseDepartment of Urology, Kurume University School of Medicine, Kurume, Japan.
Kosuke UedaDepartment of Urology, Kurume University School of Medicine, Kurume, Japan.
Hiroki SuekaneDepartment of Urology, Kurume University School of Medicine, Kurume, Japan.
Katsuaki ChikuiDepartment of Urology, Kurume University School of Medicine, Kurume, Japan.
Kiyoaki NishiharaDepartment of Urology, Kurume University School of Medicine, Kurume, Japan.
Keiichiro UemuraDepartment of Urology, Kurume University School of Medicine, Kurume, Japan.
Kazuhisa EjimaDepartment of Urology, Kurume University School of Medicine, Kurume, Japan.
Ryuji HoshinoDepartment of Urology, Kurume University School of Medicine, Kurume, Japan.
Satoshi OnishiDepartment of Urology, Kurume University School of Medicine, Kurume, Japan.
Keisuke KomiyaDepartment of Urology, Kurume University School of Medicine, Kurume, Japan.
Koichiro MurakiDepartment of Radiology, Kurume University School of Medicine, Kurume, Japan.
Chikayuki HattoriDepartment of Radiology, Kurume University School of Medicine, Kurume, Japan.
Etsuyo OgoDepartment of Radiology, Kurume University School of Medicine, Kurume, Japan.
Tatsuya IshitakeDepartment of Environmental Medicine, Kurume University School of Medicine, Kurume, Japan.
Tsukasa IgawaDepartment of Urology, Kurume University School of Medicine, Kurume, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Displacement minimization of seeds is crucial during surgery in brachytherapy; however, only a few reports have compared the operability of different seeds. TheraStrand-SL is a seed, in which TheraAGX100 is wrapped in polyglactin 910 thread, and intra-prostatic displacement is expected to be reduced compared with that of Thera-AGX100, owing to the complex shape of TheraStrand-SL. We conducted a prospective study on the operability and treatment outcomes of TheraAGX100 and TheraStrand-SL placement by a single operator. Material and methods: The study included 69 patients who received brachytherapy for prostate cancer. Endpoints were comparisons of intra- and post-treatment dose-volume histograms, seed displacement incidence rate, seed displacement distance, seed migration/dropout incidence rate, and adverse events incidence rate between TheraAGX100 ( Results: The intra-prostatic displacement incidence rate was significantly lower in the TheraStrand-SL group than in the TheraAGX100 group (TheraAGX100 group: 96.0%; TheraStrand-SL group: 11.4%). Further, the intra-prostatic displacement count per case tended to be lower in the TheraStrand-SL group than in the TheraAGX100 group. Additionally, a comparison of displacement distance per case showed that the TheraStrand-SL group (2.01 mm) had a statistically significantly shorter distance than the TheraAGX100 group (9.22 mm). No significant differences between the two groups were observed in terms of migration, explanted dropout seed count, dose-volume histograms, and adverse events incidence rate. Conclusions: Our study demonstrated the usefulness of TheraStrand-SL against intra-prostatic displacement. We expect TheraStrand-SL to have further applications in brachytherapy, including focal therapy.

Indexed as

brachytherapyprostate cancersuture-coated seeduncoated seed

Identifiers

PMID39719952
PMCPMC11664799

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.