ArticleJournal of contemporary brachytherapy2024
Where are we with fractionation schedules and prescriptions in high-dose-rate 3D planning vaginal cuff brachytherapy?
Article in Journal of contemporary brachytherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- D90 and DCancers · 2026Article
- Comparative dosimetric study of single- vs. multi-channel cylindrical applicators in vaginal brachytherapy: Implications for organs at risk and vaginal surface doses.Journal of contemporary brachytherapy · 2026Article
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Authors and funding
7 authors.
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Abstract
Purpose: Currently, there are many schedules for exclusive vaginal cuff brachytherapy (VCB). In 3D treatment planning for VCB dosimetry, parameters have not been analyzed. The aim of this study was to compare the most common schedules using dose-volume histogram metrics. Material and methods: Three different computed tomography (CT) studies for vaginal cylinders of 3.5 cm, 3 cm, and 2.5 cm were performed. Clinical target volume (CTV) was delineated for 3 cm and 4 cm of vaginal length. Twelve schedules were analyzed obtaining overall vaginal surface dose (Gy) (EQD Results: The overall vaginal surface dose and dose to CTV varied widely among the different schedules, and CTV delineation was necessary in case of surface prescription. The applicator diameter of 3.5 cm showed the best dosimetry results for vaginal surface dose. The overall D Conclusions: This dosimetry study allows for better selection of fractionation schedules, and helps to unify treatments among centers. Prospective studies are needed to establish the best schedule and CTV length in each patient using clinical data, such as late toxicity and relapses.
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