ArticleJoint diseases and related surgery2025
Risk factors and rates of revision amputation following ischemic lower major limb amputations: A 10-year retrospective analysis.
Article in Joint diseases and related surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Surgical Site Infections in Major Lower Limb Amputation (SIMBA): international multicentre study.BJS open · 2026Observational
- Predictors of Reamputation in Patients With Advanced-Stage Thromboangiitis Obliterans Ulcers: A Retrospective Cohort Study.International wound journal · 2026Article
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6 authors.
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Abstract
objectivesThis study aimed to evaluate the rates and risk factors associated with revision amputation following ischemic lower major limb amputations, focusing on cases related to peripheral arterial disease. PATIENTS AND
methodsThis retrospective study included 253 patients (174 males, 79 females; mean age: 73.1±12.2 years; range, 44 to 99 years) who underwent ischemic foot amputation between December 2012 and December 2022. Eligible patients were over 18 years old and had major lower extremity amputations due to peripheral arterial disease or chronic arterial occlusion. Exclusions were made for amputations due to diabetic foot conditions, trauma, tumors, or osteomyelitis and minor lower extremity amputations.
resultsAbove-knee amputations were the most common type of amputation, accounting for 56.5% (n=143) of cases. Revision amputations occurred in 27.3% (n=69) of patients, with significantly higher rates in those with open wounds at first admission (chi-square [χ
conclusionPatients with ischemic lower limb amputations, particularly those presenting with open wounds, are at higher risk for revision amputation. Elevated preoperative C-reactive protein levels, infections, age, and the initial level of amputation significantly impact the likelihood of reamputation.
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