Evidence map›Paper›PMID 39719683›Full record

Trial reportJournal of cosmetic dermatology2025

Focused Electric Field Technology: A Novel Myoelectrical Stimulation Technology for Noninvasive Aging Muscle Rejuvenation.

Boyang Jiang, Bingbing Chen, Jia Xu, Jieshu Luo, Min Yao

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Boyang JiangFLOSSOM Shenzhen Research Institute, Shenzhen, China.
Bingbing ChenFLOSSOM Shenzhen Research Institute, Shenzhen, China.
Jia XuFLOSSOM Shenzhen Research Institute, Shenzhen, China.
Jieshu LuoShenzhen Rawskin Dermatology, Shenzhen, China.
Min YaoDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine China, Shanghai, China.ORCID https://orcid.org/0000-0002-6946-8766

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMyoelectrical stimulation improves muscle function and reduces muscle atrophy and aging. However, research on the mechanism underlying its cosmetic effect remains limited.

aimsThe aim of this study was to evaluate the cosmetic effects of the myoelectrical stimulation provided by the wearable intelligent flexible beauty device and its focused electric field technology (FEFT) on facial skin and muscle rejuvenation. PATIENTS/

methodsWe conducted a single-blind, randomized, self-controlled clinical efficacy experiment on 31 female volunteers using the device. Using an FEFT-based platform, mice with d-galactose-induced skeletal muscle aging were subjected to surface myoelectrical stimulation of the gastrocnemius. Immunohistochemical analysis of skeletal muscles and protein immunoblotting were used to analyze the effects of FEFT.

resultsAfter 14 days of use, facial skin elasticity significantly increased, wrinkle firmness significantly decreased, and the lift height of the upper eyelid and eye corner angle significantly increased in the volunteers. Clinical evaluation showed improvements in the drooping of the upper eyelid and eye bags. Self-evaluation questionnaires indicated alleviation of facial wrinkles. These improvements were more pronounced after 28 days. In mice, FEFT alleviated aging-induced muscle fiber atrophy, muscle fiber cross-sectional area reduction, and muscle satellite cell loss. FEFT also increased the expression of myogenic factors, including myogenic differentiation 1 (MYOD1).

conclusionsFEFT exerted a skin-tightening effect by initiating myogenic processes and increasing the transformation of muscle satellite cells. Our research promotes the development of FEFT-based medical rehabilitation or cosmetic anti-aging products and provides a foundation for further application and comprehensive efficacy evaluation in human clinical settings.

Indexed as

Cosmetic TechniquesElectric Stimulation TherapyMuscle, SkeletalRejuvenationSkin AgingAdultAnimalsFemaleHumansMiceMiddle AgedSingle-Blind Methodclinical evaluationmuscle agingmuscle satellite cellsmyoelectrical stimulationmyogenic regulatory familywearable electronic devices

Identifiers

PMID39719683
PMCPMC11845949

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.