Evidence map›Paper›PMID 39719576›Full record

ArticleJournal of medical case reports2024

Strongyloidiasis mimics duodenal lymphoma in a patient with systemic lupus erythematosus and antiphospholipid syndrome: a case report.

Ayoub Basham, Sanaz Soleimani, Atash Ab Parvar, Arash Rahimi, Ebrahim Evazi, Seyed Hamid Moosavy

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Article in Journal of medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Ayoub BashamStudent Research Committee, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Sanaz SoleimaniDepartment of Pulmonology, Shahid Beheshti University of Medical Science, Tehran, Iran.
Atash Ab ParvarDepartment of Pathology, Shahid Mohammadi Hospital, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Arash RahimiDepartment of Internal Medicine, Shahid Mohammadi Hospital, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Ebrahim EvaziStudent Research Committee, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Seyed Hamid MoosavyDepartment of Gastroenterology, Shahid Mohammadi Hospital, Hormozgan University of Medical Sciences, Bandar Abbas, Iran. Seyedhamidmoosavy@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSystemic lupus erythematosus is a multi-organ autoimmune disorder that is treated by immunosuppressive agents that weaken the immune defense against opportunistic pathogens and latent infections such as strongyloidiasis. Herein, we report the case of a 43-year-old woman known to have systemic lupus erythematosus who presented with gastrointestinal symptoms, edema, and bone pain 2 months after receiving immunosuppressive treatment. CASE PRESENTATION: A 43-year-old Iranian female known to have systemic lupus erythematosus and antiphospholipid syndrome presented with abdominal pain, nausea, vomiting, and generalized edema. She was on CellCept, prednisolone, and hydroxychloroquine. The vital signs were within the normal range. On physical examination, no rash was observed on the skin. There was only a mild tenderness in epigastric region. The results of blood analysis revealed hypochromic microcytic anemia, normal leukocyte count with mild eosinophilia. Liver enzymes as well as renal function tests were within the normal range. Stool examination was negative for trophozoites, ova, or cysts of parasites. Endoscopic findings included a generalized nodular appearance of duodenum with an infiltrative mucosa in the wall of duodenum, suggesting lymphoma. The pathology report determined the diagnosis of strongyloidiasis. Cap albendazole 400 mg was administered twice a day for 2 weeks. Abdominal pain was completely relieved 1 week after starting the treatment. The patient was eventually discharged after 10 days.

conclusionThe significance of this case report is the necessity to send complete blood count and serologic assays to screen latent strongyloidiasis before receiving immunosuppressive agents in patients with systemic lupus erythematosus.

Indexed as

Antiphospholipid SyndromeLupus Erythematosus, SystemicStrongyloidiasisAdultAlbendazoleAnthelminticsDiagnosis, DifferentialDuodenal NeoplasmsFemaleHumansImmunosuppressive AgentsLymphomaAlbendazoleAnthelminticsImmunosuppressive AgentsAntiphospholipid syndromeCase reportDuodenal lymphomaNon-Hodgkin lymphomaStrongyloides stercoralisSystemic lupus erythematous

Identifiers

PMID39719576
PMCPMC11669208

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