ArticleNPJ science of food2024
Molecular mechanism of culinary herb Artemisia argyi in promoting lifespan and stress tolerance.
Article in NPJ science of food, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- 3,5-Dicaffeoylquinic Acid Delayed Aging and Promoted Oxidative Stress Tolerance via Activation of the SKN-1/Nrf2 Signaling Pathway.Food science & nutrition · 2026Article
- Effects of Scutellaria baicalensis, Folium Artemisiae argyi, and Galla Chinensis on the protein expression and resistance genes of Exiguobacterium sp. in response to gentamicin.Scientific reports · 2025Article
- Early-stage administration of hydroxytyrosol extends lifespan and delays aging in C. elegans.Biology direct · 2025Article
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Authors and funding
8 authors.
Funding
Abstract
Artemisia argyi Lévl. et Vant. (A. argyi) leaf possesses various health promoting functions contributed by its main bioactive flavonoids. In this study, the anti-aging effect and mechanism of Artemisia argyi leaf extract (AALE) were identified using Caenorhabditis elegans (C. elegans) as a model. The results showed that the AALE promoted the lifespan and stress resistance of C. elegans. It was found that the AALE boosted the expression of oxidative stress-related proteins by regulating the insulin/ IGF-1 signaling (IIS) pathway, which then activated the transcription factors DAF-16/FOXO. The results of RNA-sequence analysis indicated that the changes of genes in nematodes treated with AALE were associated with the responses against oxidative stress, cell maturation, and immune reaction, and stress. The positive results suggest that Artemisia argyi leaf could have the robust benefits for improving healthy aging as well as preventing aging-related diseases in the human body.
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Registered trials
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