Evidence map›Paper›PMID 39719383›Full record

ArticleMuscle & nerve2025

Physical Activity Correlates With Skeletal Muscle MRI Findings in Individuals With Duchenne Muscular Dystrophy.

Jaclyn Tamaroff, Nicholas Joy, Bruce Damon, Larry W Markham, Thomas Donnelly, Karry Su, Maciej S Buchowski, Kimberly Crum, James C Slaughter, Meng Xu and 2 more

Abstract read
In one paragraph

Article in Muscle & nerve, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Six-Minute Activity-95Pediatric neurology · 2026
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jaclyn TamaroffDivision of Pediatric Endocrinology and Diabetes, Vanderbilt University Medical Center, Nashville, Tennessee, US.ORCID https://orcid.org/0000-0002-3630-9937
Nicholas JoyDivision of Pediatric Cardiology, Vanderbilt University Medical Center, Nashville, Tennessee, US.
Bruce DamonVanderbilt University Institute of Imaging Science and the Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, US.
Larry W MarkhamDivision of Pediatric Cardiology, Riley Hospital for Children and Indiana University School of Medicine, Indianapolis, Indiana, US.
Thomas DonnellyDivision of Pediatric Cardiology, Vanderbilt University Medical Center, Nashville, Tennessee, US.
Karry SuDivision of Pediatric Cardiology, Vanderbilt University Medical Center, Nashville, Tennessee, US.
Maciej S BuchowskiDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, US.
Kimberly CrumDivision of Pediatric Cardiology, Vanderbilt University Medical Center, Nashville, Tennessee, US.
James C SlaughterDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, US.
Meng XuDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, US.
W Bryan BurnetteDivision of Pediatric Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, US.ORCID https://orcid.org/0000-0002-7637-5330
Jonathan SoslowDivision of Pediatric Cardiology, Vanderbilt University Medical Center, Nashville, Tennessee, US.

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Phase 2 Study of Theophylline for the Treatment of PsuedohypoparathyroidismR01DK118407 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SHOEMAKER, ASHLEY HALL · 2021 to 2025
$3.2M
Development and Application of Muscle Diffusion Tensor MRIR01AR073831 · NIAMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DAMON, BRUCE M. · 2019 to 2024
$2.1M
Multiparametric Classification of Muscle Damage in Inflammatory MyopathyR01AR057091 · NIAMS · VANDERBILT UNIVERSITY · PI DAMON, BRUCE M. · 2009 to 2013
$1.7M
Quantitative Assessment of Cardiac Disease in Duchenne Muscular DystrophyK23HL123938 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SOSLOW, JONATHAN HARVEY · 2014 to 2018
$829k
Development of a Multimodal Biomaker Platform for Predictive Risk Stratification of Cardiac Disease in Duchenne Muscular DystrophyR56HL141248 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SOSLOW, JONATHAN HARVEY · 2018 to 2018
$769k
American Heart AssociationFDA HHS R01 FD006649FightDMDNCATS NIH HHS UL1 TR002243NHLBI NIH HHS K23 HL123938NHLBI NIH HHS R56 HL141248NIAMS NIH HHS R01 AR057091NIAMS NIH HHS R01 AR073831NIDDK NIH HHS R01 DK118407
6 · The paper itself

Abstract

INTRODUCTION/

aimsSkeletal muscle magnetic resonance imaging (MRI) is a validated noninvasive tool to assess Duchenne muscular dystrophy (DMD) progression. There is interest in finding DMD biomarkers that decrease the burden of clinical trial participation, such as wearable devices. Our aim was to evaluate the relationship between activity, via accelerometry, and skeletal muscle MRI, particularly T

methodsDMD children and young adults completed skeletal muscle MRI and were asked to wear an accelerometer on the dominant wrist for 7 days. MRI data included fat-suppressed transverse relaxation time (T

resultsParticipants (n = 22; median age 11.4 years, 41% ambulatory) wore the accelerometer for a median of 7 days. Longer T DISCUSSION: In individuals with DMD, longer T

Indexed as

ExerciseMagnetic Resonance ImagingMuscle, SkeletalMuscular Dystrophy, DuchenneAccelerometryAdolescentAdultChildFemaleHumansMaleYoung AdultaccelerometryDuchenne muscular dystrophyoutcome measurepediatricsskeletal muscle MRI

Identifiers

PMID39719383
PMCPMC11799400

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.