ArticleContemporary clinical trials2025
The "Mammograms Available Due to Resources and Education" (MADRE) Study: Rationale and Design.
Article in Contemporary clinical trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05841355 (MADRE), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
MADRE (Mammograms Available Due to Research and Education)
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Authors and funding
18 authors.
Funding
Abstract
backgroundLatinas suffer disproportionately from breast cancer, partially due to lower uptake of guideline-concordant breast cancer screening. We describe the design of a study to compare two approaches addressing this important public health problem. DESIGN/
methodsWe are conducting a 5-year randomized controlled trial. From a federally qualified health center network and through community outreach, we are recruiting 400 Latinas from Chicago who are non-adherent with United States Preventive Services Task Force breast cancer screening guidelines. Participants are randomized at a 1:1 ratio to receive one of two phone-based interventions (empowerment, education) administered across 3 weekly sessions. Both interventions provide information about breast cancer early detection. The empowerment intervention additionally teaches participants to share information about breast cancer screening with family and friends, while the education intervention educates patients about breast cancer prevention. Non-adherent Latina participants recruit family and friends eligible for breast cancer screening to take part in the study as network members. Network members do not participate in the intervention. Primary outcomes are initial (any mammogram post-enrollment) and repeat (measured at two-year intervals after enrollment) breast cancer screening among intervention participants and network members. Additionally, we will use multi-level structural equation models to assess potential mediators of the impact of the interventions. DISCUSSION: This study will inform the development of empowerment approaches to increase participation in breast cancers screening among Latinas and reduce health disparities. NCT05841355.
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