Evidence map›Paper›PMID 39718967›Full record

ArticleThe Journal of infectious diseases2025

Staphylococcus aureus Tetracycline Resistance and Co-resistance in a Doxycycline Postexposure Prophylaxis-Eligible Population.

Rachel Mittelstaedt, Sanjat Kanjilal, David Helekal, Gregory K Robbins, Yonatan H Grad

Abstract read
In one paragraph

Article in The Journal of infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

  • Update of
    2024
5 · Who and what money

Authors and funding

5 authors.

Rachel MittelstaedtDivision of Infectious Diseases, Department of Medicine, Massachusetts General Hospital.ORCID 0009-0005-7199-3382
Sanjat KanjilalDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Healthcare Institute.ORCID 0000-0002-1221-5725
David HelekalDepartment of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health.
Gregory K RobbinsDivision of Infectious Diseases, Department of Medicine, Massachusetts General Hospital.
Yonatan H GradDepartment of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health.ORCID 0000-0001-5646-1314

Funding

PROGRAM FOR AIDS CLINICAL RESEARCH TRAINING (PACRT)T32AI007433 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI MARK J SIEDNER · 1992 to 2026
$11.4M
Genomics approaches to elucidating pathways to antibiotic resistance in Neisseria gonorrhoeaeR01AI132606 · NIAID · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Yonatan H Grad · 2017 to 2026
$3.8M
CDC HHSNIAID NIH HHS R01 AI132606NIAID NIH HHS T32 AI007433
6 · The paper itself

Abstract

Among doxycycline postexposure prophylaxis (doxy-PEP)-eligible men, Staphylococcus aureus tetracycline nonsusceptibility is more prevalent than in the overall population and is associated with resistance to trimethoprim-sulfamethoxazole and clindamycin. Doxy-PEP may select for multidrug-resistant S aureus, underscoring the importance of surveillance.

Indexed as

Anti-Bacterial AgentsDoxycyclinePost-Exposure ProphylaxisStaphylococcal InfectionsStaphylococcus aureusTetracycline ResistanceAdultAgedDrug Resistance, Multiple, BacterialHumansMaleMicrobial Sensitivity TestsMiddle AgedTrimethoprim, Sulfamethoxazole Drug CombinationYoung AdultAnti-Bacterial AgentsDoxycyclineTrimethoprim, Sulfamethoxazole Drug Combinationdoxycycline postexposure prophylaxisdoxy-PEPStaphylococcus aureus

Identifiers

PMID39718967
PMCPMC11998573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.