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ArticleHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2025

The Relationship Between Blood Pressure and Heart Rate Response During Exercise Testing with Microcirculation Indices.

Ioannis Liatakis, Kyriakos Dimitriadis, Eleni Manta, Ioannis Andrikou, Nikolaos Pyrpyris, Fotios Tatakis, Dimitrios Konstantinidis, Konstantinos Thomopoulos, Antonios Manolis, Dimitrios Tousoulis and 1 more

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Article in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Ioannis LiatakisFirst Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration Hospital, Vas. Sofias 114, 11527, Athens, Greece.
Kyriakos DimitriadisFirst Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration Hospital, Vas. Sofias 114, 11527, Athens, Greece. dimitriadiskyr@yahoo.gr.ORCID http://orcid.org/0000-0003-3186-8905
Eleni MantaFirst Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration Hospital, Vas. Sofias 114, 11527, Athens, Greece.
Ioannis AndrikouFirst Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration Hospital, Vas. Sofias 114, 11527, Athens, Greece.
Nikolaos PyrpyrisFirst Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration Hospital, Vas. Sofias 114, 11527, Athens, Greece.
Fotios TatakisFirst Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration Hospital, Vas. Sofias 114, 11527, Athens, Greece.
Dimitrios KonstantinidisFirst Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration Hospital, Vas. Sofias 114, 11527, Athens, Greece.
Konstantinos ThomopoulosFirst Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration Hospital, Vas. Sofias 114, 11527, Athens, Greece.
Antonios ManolisFirst Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration Hospital, Vas. Sofias 114, 11527, Athens, Greece.
Dimitrios TousoulisFirst Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration Hospital, Vas. Sofias 114, 11527, Athens, Greece.
Konstantinos TsioufisFirst Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration Hospital, Vas. Sofias 114, 11527, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHypertension is associated with changes in microcirculation, while increased blood pressure (BP) during exercise stress testing has been correlated with adverse outcomes.

aimTo evaluate the relationship of microcirculation with exercise BP response in hypertensive individuals.

methods105 hypertensive individuals underwent exercise stress testing and nail-fold videocapillaroscopy assessment, in order to evaluate the relationship of BP response to exercise with capillary density.

resultsA significant negative correlation between diastolic BP at 1-minute recovery and capillary density was revealed (Pearson's r = -0.365, p = 0.043). A significant negative correlation was also observed between capillary density and peak heart rate (HR) (Pearson's r = -0.364, p = 0.024) and HR increase from stage 1 to 2 (Pearson's r = -0.746, p = 0.013).

conclusionCapillary rarefaction is associated with an abnormal BP and HR response to exercise, highlighting the role of microcirculation in BP regulation during exercise.

Indexed as

Blood PressureCapillariesExerciseExercise TestHeart RateHypertensionMicrocirculationMicrovascular RarefactionNailsAdultAgedCross-Sectional StudiesFemaleHumansMaleMicroscopic AngioscopyCapillaroscopyCapillary rarefactionExercise stress testHypertensionMicrocirculation

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.