Evidence map›Paper›PMID 39718679›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2025

Comparison of six different methods used in detection of colistin resistance in extensively drug-resistant K. pneumoniae, A. baumannii and P. aeruginosa isolates with the reference method broth microdilution method.

Özlem Aydemir, Sema Çetin, Nilay Can, Gökçen Ormanoğlu, Mehmet Köroğlu

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Prevalence of Colistin-ResistantMicroorganisms · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Özlem AydemirFaculty of Medicine, Department of Medical Microbiology, Sakarya University, Sakarya, Turkey. ozlemaydemir@sakarya.edu.tr.ORCID http://orcid.org/0000-0003-4533-6934
Sema ÇetinFaculty of Medicine, Department of Medical Microbiology, Sakarya University, Sakarya, Turkey.
Nilay CanFaculty of Medicine, Department of Medical Microbiology, Sakarya University, Sakarya, Turkey.ORCID http://orcid.org/0009-0008-7309-1886
Gökçen OrmanoğluFaculty of Medicine, Department of Medical Microbiology, Sakarya University, Sakarya, Turkey.ORCID http://orcid.org/0000-0002-2240-460X
Mehmet KöroğluFaculty of Medicine, Department of Medical Microbiology, Sakarya University, Sakarya, Turkey.ORCID http://orcid.org/0000-0001-8101-1104

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to evaluate the agreement of different methods with the reference method in the detection of colistin resistance in extensively drug-resistant K. pneumoniae, A. baumannii and P. aeruginosa isolates. MATERIALS AND

methodsK. pneumoniae, A. baumannii and P. aeruginosa isolates were included in the study. All isolates were subjected to colistin susceptibility testing with seven different methods. All results were compared with broth microdilution results. Categorical agreement (CA), very majorl error (VME) and major error (ME) rates were calculated for the tested methods.

resultsIn all methods, VME and ME rates were found to be above the acceptable performance limit for all strains. Although VME rates were above the target value in all strains, the lowest VME rates were detected in MRRP-NP with 12.5%. Among all isolates, the lowest ME rate was obtained in MCLDE with 10% and the highest ME rate was detected in VITEK 2

conclusionsThe results obtained in this study show that the methods used in colistin susceptibility testing still need standardization. There is an urgent need for a colistin susceptibility testing method that is easy to apply, inexpensive and suitable for routine use.

Indexed as

Acinetobacter baumanniiAnti-Bacterial AgentsColistinDrug Resistance, Multiple, BacterialKlebsiella pneumoniaePseudomonas aeruginosaDrug Resistance, BacterialHumansMicrobial Sensitivity TestsAnti-Bacterial AgentsColistinAntibiotic resistanceantibiotic susceptibility testcolistincolistin susceptibility test method

Identifiers

PMID39718679

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.